Nigrostriatal pathway - Study guides, Class notes & Summaries
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NR 546 Antipsychotics Table Week 3 Assignments.
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NR 546 Antipsychotics Table Week 3 Assignments. 
Drug name Indication 
Target symptoms: state if positive or negative effect 
Potency (if noted. receptor occupancy if noted) 
Neurotransmitter(s) affected 
Half-life (T1/2), 
metabolism (CYP 
450 enzyme) 
Notable side effects (associate to pathway or NT) 
Typical antipsychotics (conventional) 
Haloperidol Target symptoms: 
Manifestations of psychotic disorders 
Tics and vocal utterances in Tourette’s Syndrome 
Second-line treatment of severe beh...
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Maryville Psychopharmacology, Exam 1 Review
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How many dopamine pathways in the brain? - Answer - 5 but only 4 associated with schizophrenia 
 
Nigrostriatal Dopamine Pathway controls - Answer - motor function and movement (part of EP NS) 
 
Nigrostriatal Dopamine Pathway dopamine excess - Answer - Hyperkinetic movements such as tics/dyskinesias 
 
mesolimbic dopamine pathway controls - Answer - Pleasure, reward, euphoria of drug abuse and reinforcing behavior 
 
Mesolimbic dopamine pathway excess - Answer - delusions and hallucinations - p...
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Regis College PSYCH 643 - All Weeks Quizzes - Questions with Verified Answers
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Week 3 Quiz 
#1 is C. 
1. Volume neurotransmission refers to? 
The diffusion of neurotransmitter to nearby neurons. 
2. Retrograde neurotransmissions refers to? 
The flow of neurotransmitter from postsynaptic neuron to presynaptic neuron 
3. Use the following CYP450 table to hypothesize drug interactions and their clinical 
significance for a patient on clozapine who carbamazepine, a mood stabilizer? 
Clozapine levels would decrease, placing the patient at risk for re-emergence of 
psychotic sym...
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Exam 1: NURS 660/ NURS660 (Latest 2024/ 2025 Update) Psychopharmacology and Advanced Mental Health Guide | Qs & As| 100% Correct| Grade A (Verified Answers)- Maryville
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Exam 1: NURS 660/ NURS660 (Latest 2024/ 2025 Update) Psychopharmacology and Advanced Mental Health Guide | Qs & As| 100% Correct| Grade A (Verified Answers)- Maryville 
 
Q: Five Different Dopamine Pathways in the brain 
 
 
Answer:: 
-Nigrostriatal Dopamine Pathway 
-Mesolimbic dopamine pathway 
-Mesocorticol dopamine pathway 
-Tuberoinfundibular dopamine pathway 
-Thalamic dopamine pathway 
 
 
 
Q: Nigrostriatal pathway 
 
 
Answer:: 
Projects from the substantia nigra to the basal ganglia o...
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NURS 660 Exam 1 Latest Exam Questions & Answers, All Answers Explained
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NURS 660 Exam 1 Latest Exam Questions & Answers, All Answers Explained-1.	Identify the emerging neurobiological hypothesis of schizophrenia. 
o	The hypothesis: (focus on the most detail with the Dopamine Theory) 
	The only pharmacological treatment that we have are dopamine (D2 receptors) and serotonin (5HT2A) 
	Dopamine Theory 
▪	Hyperactive dopamine at D2 receptors in the mesolimbic pathway 
 In the mesolimbic pathway is responsible for the positive symptoms; the hypoactivity is responsible...
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ANCC PMHNP Exam Prep
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mesocortical pathway – 
executive function: attention, focus, depression 
nigrostriatal pathway – 
from substantia nigra (brainstem) to striatum (muscles): Parkinson's 
mesolimbic pathway – 
projects to nucleus accumbens (part of limbic system). Pleasure, reward, 
positive symptoms of schizophrenia: Addiction, gambling 
Tuberoinfundibular pathway – 
regulation of prolactin (acts on pituitary). Hypersexuality in mania 
Dopamine – 
produced in substania nigra and VTA. D2 & D4 receptors ...
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ANCC PMHNP Exam Prep Question with complete solution 2023
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ANCC PMHNP Exam Prep Question with complete solution 2023mesocortical pathway 
executive function: attention, focus, depression 
 
 
 
nigrostriatal pathway 
from substantia nigra (brainstem) to striatum (muscles): Parkinson's 
 
 
 
mesolimbic pathway 
projects to nucleus accumbens (part of limbic system). Pleasure, reward, positive symptoms of schizophrenia: Addiction, gambling 
 
 
 
Tuberoinfundibular pathway 
regulation of prolactin (acts on pituitary). Hypersexuality in mania 
 
 
 
Dopam...
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LMR - Georgette's flashcard 2023/2024
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LMR - Georgette's flashcard 2023/2024 
 
 
LMR - Georgette's flashcard 2023/2024 
Terms in this set (526) 
 
 
What drugs should be avoided with Kava Kava?	 
Alprazolam 
CNS depressants (e.g., phenobarbital, zolpidem) 
 
What is the normal range for TSH?	 
0.5 - 5.0 mu/L 
 
What are lab values in Hyperthyroidism	 
Decreased TSH Increased T4 and T3 
 
What are labs in Hypothyroidism?	 
Increased TSH Decreased T4 and T3 
	 
Heat intolerance 
What are 5 primary symptoms of	Agitation, Anxiety, Irr...
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NR-546 Advanced Pharmacology Psychopharmacology for the Psychiatric-Mental Health Nurse Practitioner
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How does the orbitofrontal cortex (OFC) affect the amygdala? - inhibits and activates the amygdala 
Wernicke's area is associated with which of the following? - speech comprehension 
The limbic system is associated with which of the following - emotion and learning 
Which brain structure is most associated with long term memory? - hippocampus 
When prescribing psychotropic medications, the PMHNP knows that these medications work within which specific areas? - mood 
Which of the following are in...
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Exam (elaborations) NURS 660
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dopamine hypothesis - ANSWER the theory that schizophrenia results from excessive 
activity of the neurotransmitter dopamine 
dopamine hypothesis- nigrostriatal pathway - ANSWER The nigrostriatal dopamine 
pathway that projects from the substantia nigra to the basal ganglia or striatum, is part 
of the extrapyramidal nervous system and controls motor function and movement. 
Mesolimbic dopamine hypothesis: Hyperactivity of dopamine neurons in the mesolimbic 
dopamine pathway cause what sympto...
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