Malignant hypert - Study guides, Class notes & Summaries

Overview - Rare inherited disorder in which a severe life-threatening reaction occurs due to inhaled anesthesia gases or a muscle relaxant called succinylcholine Hypermetabolic state that results in a rapid rise in body temperature and severe muscle contraction Possibly resulting in death if untreated Overview-Pathophysiology - A defect in calcium regulation results from a triggering anesthetic agent due to an inherited disorder of the musculoskeletal system. This calcium regulation defect ...

What is malignant hyperthermia? - It is a rare, life-threatening, hypermetabolic skeletal muscle disorder. How does malignant hyperthermia occur? - Triggering agents induce significantly increased calcium concentrations in the skeletal muscle cells. Sustained muscle contraction occurs. Energy-dependent calcium channels try to remove the excess calcium which increases the metabolism of the skeletal muscles. The increased metabolism depletes ATP stores and causes lactic acidosis. The acidosis...

Malignant hyperthermia - is a life-threatening familial hypermetabolic disorder of skeletal muscle that can be precipitated by specific anesthetic agents. characteristics of MH - tachycardia, tachypnea, hyperthermia, generalized muscle rigidity, acidosis, and increasing ETCO2 levels. how fast does the temperature increase with MH? - Rapid increase in temperature by as mush as 1o C every 5 mins. how does acidosis result from MH? - is a result of increased skeletal muscle metabolism that may...

Arrhythmia - Irregular heartbeat. Improper beating of the heart. Hypercapnia - Excessive carbon dioxide in the bloodstream Hyperkalemia - Condition in which there is too much potassium in the blood. Metabolic Acidosis - A pH imbalance in which the body has accumulated too much acid Myoglobinuria - Muscle protein in the urine. Usually associated with rhabdomyolysis or muscle destruction. Cola colored urine. Rhabdomyolysis - Condition in which skeletal muscle is broken down, releasing muscl...

What is the incidence of malignant hyperthermia in children? Adults? What is the mortality rate for malignant hyperthermia? - The incidence of malignant hyperthermia is 1 in 15,000 anesthetics in children and 1 in 50,000 in adults, The mortality rate is 10%. What are eleven clinical manifestations of malignant hyperthermia? - (1) Hypercarbia, (2) tachycardia, (3) tachypnea, (4) hyperthermia, (5) hypertension, (6) cardiac dysrhythmias, (7)acidosis (metabolic), (8) hyperkalemia, (9) skeletal ...

Malignant hyperthermia triggers - Succinylcholine Volatile anesthetics Disease associated with malignant hyperthermia - Central core disease Duchenne muscular dystrophy Myotonic dystrophy Osteogenesis imperfecta Myelomeningocele Strabismus Signs/symptoms of malignant hyperthermia (also name the most sensitive, specific and earliest) - 1) Tachycardia (earliest) 2) Increased ETCO2 despite adequate ventilation (most sensitive/specific) 3) Rigidity 4) Elevated temperature 5) Acidosis 6...

Malignant Hyperthermia - Genetic disorder Affects between 10,000 and 50,000 individuals. Risk of potentially life-threate Onset - In operating room: -tachypnea (rapid breathing) -low plasma [o2] -high plasma [co2] -tachycardia (rapid heart rate) -hyperthermia (rising body temp) can be as rapid as 1 degree every 5 mins. -rigidity, sweating and dramatic swings in blood pressure. Onset usually during anesthesia, but can occur several hours later. Untreated - Pt develops respiratory and l...

DAANCE practice test/2023 LATEST UPDATE/GUARANTEED SUCCESS Signs of malignant hyperthermia - ANSWER-Tachycardia, CO2 retention, muscle rigidity, increase in body temp, lethal arrythmia Tx for malignant hyperthermia - ANSWER-EMS, O2, dantrolene, cold saline IV, ice packs-groin, axilla,neck What tyoe of med is methohexital/brevital - ANSWER-Barbiturate Side effects of brevital - ANSWER-Apnea on induction, muscle twitching, hiccups, decrease in BP, increase in HR, laryngospasm, bronchos...

MSK Practice Exam Questions With Correct Answers Explained 2023