Kuby immunology ch - Study guides, Class notes & Summaries

These are specialized sites in the gut and other mucosal tissues that coordinate the encounter of antigen with antigen-specific lymphocytes and their development into effector and memory cells. ex. spleen, lymph nodes - ANSWER secondary lymphoid organs These organs (thymus and bone marrow) regulate the development of immune cells from immature precursors. - ANSWER primary lymphoid organs It gives rise to all functionally specialized, mature blood cells (red blood cells, granulocytes, macro...

Tolerance - ANSWER A stage of immunologic unresponsiveness to particular antigens or sets of anitgens; Typically, an organism is unresponsive or tolerant to self antigens Sequential Epitopes - ANSWER Two or more antigenic determinants formed by a single sequence of amino acids. Nonsequential Epitopes - ANSWER Epitopes that are far apart in the primary sequence of the polypetide chain, but close together in the teritary structure of the molecules.

1. Describe the clonal selection hypothesis. (19) - ANSWER one cell recognize a specific antigen and it divides 2. What is a t-dependent antigen? 21 min - ANSWER Conentional response leads to HEV Determined importance of T cells in the production of antibodies Mice were radiated not reconstituted with anything they werent able to make antibodies Mice were radiated reconstituted with bone marrow cell alone they werent able to make antibodies 3. What is a t-independent antigen? What is the...

Immunology has allowed for: - ANSWER Vaccine development, transplantation, pharmaceutical drug development. Immune system is intertwined with many other systems and functions such as: - ANSWER endocrine, nervous, metabolic systems and homeostasis. Immunis: latin for - ANSWER exemp

Viruses, like many good pathogens, have adapted to survive in their hosts. Which of the following scenarios would be MOST favorable to viral transmission and long term survival of the viral species? A. Virus X enters a host cell, produces many progeny viruses (virions), and lyses the host cell. B. Virus X enters the host cell and merges viral DNA with the host DNA so that the virus is copied into all progeny host cells. C. Virus X enters the host cells, merges viral DNA with the host DNA un...

primary lymphoid organs - ANSWER organs in which lymphocyte precursors mature into antigenically committed , immunocompetent cells. In mammals, the bone marrow and thymus are the these organs in which B-cell and T-cell maturation occur, respectively. secondary lymphoid organs - ANSWER organs and tissues in which mature, immunocompetent lymphocytes encounter trapped antigens and are activated into effector cells. In mammals, the lymph nodes, spleen, and mucosal-associated lymphoid tissue (MA...

1. Committed lymphocyte progenitors originate in the: A. thymus. B. bone marrow. C. spleen. D. lymph node. E. brain. - Answer: B Section: Early Thymocyte Development Difficulty: 1 Hint: All blood cells originate in the same anatomical location. 2. Hematopoietic stem cells cultured in the presence of which receptor differentiate into T cells rather than B cells? A. CD4 B. CD8 C. Notch-ligand D. B7-1 E. CD3 - Answer: C Section: Early Thymocyte Development Difficulty: 1 Hint: Mark...

effector response - ANSWER elimination or neutralization of the invader memory response - ANSWER a more rapid and heightened immune reaction upon later attack innate immunity - ANSWER molecular and cellular mechanisms predeployed before an infection and poised to prevent or eliminate it

Kuby Immunology Exam 1 Ch's 1-6

Kuby Immunology Exam 1 (Ch. 1-5).