Gene mutations - Study guides, Class notes & Summaries

Ras signaling - GTPase - promotes growth and proliferation - mutated in 20-30% of all cancers - point mutations are most common G12V mutation - blocks GAP binding - locks RAS in active state, promoting proliferation Q61K mutation - raises activation energy of GTP hydrolysis - blocking hydrolysis, keeping RAS active Hallmarks of cancer 1) self-sufficiency in growth signals 2) insensitivity to anti-growth signals 3) unstable DNA 4) metastasis 5) evasion of apoptos...

OPENSTAX MICROBIOLOGY TEST BANK OpenStax Microbiology THIS TEST BANK COVERS ALL CHAPTERS 1-26 OF THE BOOK 1 An Invisible World 1.1 What Our Ancestors Knew 1.2 A Systematic Approach 1.3 Types of Microorganisms 2 How We See the Invisible World 2.1 The Properties of Light 2.2 Peering Into the Invisible World 2.3 Instruments of Microscopy 2.4 Staining Microscopic Specimens 3 The Cell 3.1 Spontaneous Generation 3.2 Foundations of Modern Cell Theory 3.3 Unique Characteristics of Prokaryotic Cells 3.4 ...

RNAS-C Exam 4 Practice Test 75 Questions with Verified Answers A couple expecting their second child is worried about Rh incompatibility. Their first child was Rh+. They have their blood typed. Which result would be cause for alarm? A) both parents Rh- B) both parents Rh+ C) man Rh- and woman Rh+ D) man Rh+ and woman Rh- - CORRECT ANSWER D) man Rh+ and woman Rh- Research indicates that allergies may actually be due to a mutation in the gene that encodes a skin protein called __________...

TEST BANK ESSENTIALS OF PATHOPHYSIOLOGY (4TH EDITION BY PORTH) CONTENTS Chapter 01 - Cell Structure and Function .......................................................................................................................... 2 Chapter 02 - Cellular Responses to Stress, Injury, and Aging .......................................................................................... 7 Chapter 03 - Inflammation, the Inflammatory Response, and Fever ..............................................

ASU BIO 340 Exam 3 | WITH QUESTIONS AND ANSWERS 100% VERIFIED What will be the effect on transcription when an inhibitor is in play? A. Allow transcription B. Prevent transcription - B Explanation: An inhibitor prevents activator from binding to DNA; activators are used in positive regulation (increasing transcription) - thus, the inhibitor prevents the activator from positive regulating (increasing) transcription. What will be the effect on transcription when an inducer is in play? A. A...

Oncogene - ANSWER-A gene that causes or contributes to the development of cancer Hallmarks of Cancer - ANSWER-Sustaining proliferative signaling Evading growth suppressors Activating invasion and metastasis Enabling replicative immortality Inducing angiogenesis Resisting cell death In vivo oncogenic evidence - ANSWER-Cause cancer when activated in a transgenic animal Render nontumorigenic cells tumorigenic Knock down or knock out in tumorigenic cells renders the cells nontumorigenic...

What modification neutralizes the charges on histones and looses up the interactions between histones and DNA? - Answer- ACETYLATION Two types of post-transcriptional modifications that take place in the mRNA of eukaryotes - Answer- the addition of a CAP at the 5' end of the transcript and the addition of a POLY A sequence at the 3' end of the message Nucleic acid blotting is widely used in recombinant DNA technology. In a Southern blot one generally - Answer- Hybridizes filter-bound DNA...

Sex-Linked recessive. Since males only have one X and one Y, if the affected chromosome has the illness, it will be expressed. Which type of genetic disease affects males more frequently than females? Intellectual disability and fetal miscarriage. Chromosome abnormalities are the leading known cause of intellectual disability and fetal miscarriage. In which two conditions are chromosomal abnormalities the leading known cause? Chorionic villus sampling (CVS), amniocentesis, and pr...

Test Bank for Primary Care: Interprofessional Collaborative Practice 6th Edition by Buttaro. All Chapters 1- 228 Questions And Answers in 260 Pages. All Answers Are Correct. Primary Care : A Collaborative Practice, 6th Edition Terry Buttaro, JoAnn Trybulski, Patricia Polgar-Bailey Joanne Sandberg-Cook Chapter 1: The Evolving Landscape of Collaborative Practice Test Bank Multiple Choice 1. Which assessments of care providers are performed as part of the Value Based Purchasing initiative? Select a...

Table of Contents PART I Basic Principles: How Traits Are Transmitted 1 Mendel’s Principles of Heredity 2 Extensions to Mendel’s Laws 3 Chromosomes and Inheritance 4 Sex Chromosomes 5 Linkage, Recombination, and Gene Mapping PART II What Genes Are and What They Do 6 DNA Structure, Replication, and Recombination 7 Mutation 8 Using Mutations to Study Genes 9 Gene Expression: The Flow of Information from DNA to RNA to Protein PART III Analysis of Genetic Information 10 Digital Analysis of DNA 1...