Competitive antagonist - Study guides, Class notes & Summaries

Receptor Macromolecule whose biological function changes when a drug binds to it What are the link between chemical actions and biological function? Receptors Emax maximum effect of a drug What happens when Emax is reached? Emax occurs when all receptors are bound What is in indication that spare receptors are present? When Emax is reached before all receptors are bound Agonist has affinity for a receptor as well as intrinsic activity at the receptor ...

Which one of the following choices is a competitive antagonist for aldosterone that is sometimes used in treatment of congestive heart failure? A - Hydrochlorothiazide B - Furosemide C - Mannitol D - Acetazolamide E - Spironolactone correct answers Spironolactone What is the average length of estrus in the cat? A - 2-3 days B - 4-5 days C - 9-10 days D - 6-7 days E - 21 days correct answers 6-7 days What is the proper name for the swine kidney worm? A - Capillaria plica B...

Which one of the following choices is a competitive antagonist for aldosterone that is sometimes used in treatment of congestive heart failure? A - Hydrochlorothiazide B - Furosemide C - Mannitol D - Acetazolamide E - Spironolactone - Spironolactone What is the average length of estrus in the cat? A - 2-3 days B - 4-5 days C - 9-10 days D - 6-7 days E - 21 days - 6-7 days

1. Pharmacodynamics is: A. The science that examines the interrelationship of the physiochemical properties of the drug and the route of administration on the rate and extent of systemic drug absorption B. The science of the kinetics of drug absorption, distribution and elimination C. The part of pharmacology, which deals with what a drug does to the body D. The science, which deals with the physiochemical properties of the drug that allow it to be designed into dosage forms E. A and B - ...

Acetaminophen (Ans- interacts with phenytoin and carbamazepine - increase rate of liver toxicity, after acetaminophen overdose. Adenosine (Ans- Dipyridamole blocks cellular uptake of adenosine. Theophylline is a competitive antagonist at adenosine receptors. Epinephrine (Ans- Beta-blockers can induce widespread vasoconstriction. Alpha blockers (Ans- Other blood pressure lowering drugs increase risk of first-dose hypotension and hypotension risk generally thereafter. Aminoglyc...

PHARMACOLOGY, TOXICOLOGY, PHARMACOKINETICS 1. Two dose-response curve response plotted on the same graph showed sigmoid curves having the same slope and height. T curve is located to the right of the A curve. Which of the following statements is/are correct regarding curves A an: I. A is more effective than B II. A is more potent than B III. A and B have the same ceiling dose IV. B is the graph produced when A is given with its competitive antagonist V. B is the graph produced when A is given wi...

Competitive Antagonists Compete with neurotransmitters for access to orthosteric binding sites on receptors *block responses to agonists How do competitive antagonists affect DRC? Cause a rightward shift How do you reverse the effects of a antagonists? Add more exogenous agonist or increase the concentration of endogenous for that receptor in order to overcome that antagonism When an antagonist competes with an agonist, does the antagonist always win and bind to orthos...

NR565 Midterm Study Guide with Complete Solutions APRN prescribing role Prescriptive authority for nurse practitioners also regulates prescribing rights beyond medications and controlled substances. These rights include therapeutic devices and services and are outlined in state practice laws and regulations and include Durable Medical Equipment (DME) such as wheelchairs, power scooters, hospital beds, portable oxygen equipment, handicap placards, etc. and medical services such as Physi...

NRSC 2125 - Midterm 3, Exam Review Questions and answers, rated A+ What is a drug agonist (full and partial)? - -drug agonist - chemical that binds to & activates a receptor to produce a biological response full agonist - produces the maximum response partial agonist - produces less than the maximum response What is a drug antagonist (competitive/non-competitive)? - -drug antagonist - chemical that binds to & blocks a receptor (does NOT activate), thus blocking or dampening a biologica...

Agonist - Competitive inhibition, binds to active site and causes a signal response in receptive tissue. Antagonist (blocker) - Competitive inhibitor, binds to active site so signal molecules cannot bind but causes no response in receptive tissue, can bind and release eventually. Apply your understanding of channels and synapses to predict how various neurotoxins affect nervous function. - Neurotoxins block receptor proteins on the post-synaptic neuron. Example: tetrodotoxin form Fugu fish...