Classical pathways - Study guides, Class notes & Summaries

1st Line of Defense - Chemical, Mechanical, and physical barriers 2nd Line of Defense - Inflammation Activate Acquired Immunity - produced by individual after natural exposure to antigens or after immunization Acute inflammation - self-limiting, continues until host is gone, result from vascular changes and the subsequent leakage of circulating components in the tissue Acute pain - protective mechanism, immediately harmful to body and mobilizes individual to take action against it, lastin...

IgG Sublcass most efficient in initiating classical complement - IgG3 Steric exclusion of water molecules is the mechanism of this enhancement - PeG Stage of Complement activation common to all three pathways - Activation Phase-C3 convertase IgM agglutination is enhanced at what temperature - Lower than RT Activation of C1 in classical pathway requires - Calcium What antigens are destroyed by Enzymes - MNSs Fya and Fyb A shot containing killed virus which causes the body to produce antibod...

What are the 4 sources of infection? ~~> Bacteria, viruses, fungi, parasites What does the immune system need to be able to do for an effective immune response? ~~> 1- Be able to recognise and respond to any invading organism 2- Not over react to benign or self 3- Be able to direct different effector mechanisms against different pathogens approximately how many bacteria are their and how many are named? ~~> 10^9 bacteria and 30000 named What is specific/adaptive immunity? ~...

NU 545 CH 7 EXAM QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS GRADED A++ Cathelicidins Family of antimicrobial peptides that in humans has one member. Defensins antimicrobial peptides that inhibit microbial growth Mannose-binding lectin (MBL) soluble acute-phase protein in the blood that binds to mannose residues on pathogen surfaces and, when bound, activates the complement system by the lectin pathway Resistin-like molecule beta Found in intestinal goblet cells, where it appears to pr...

ADVANCED PATHOPHYSIOLOGY FINAL EXAM WITH COMPLETE SOLUTIONS What is the most common cause of Down syndrome? a. Paternal nondisjunction b. Maternal translocations c. Maternal nondisjunction d. Paternal translocation - C What does activation of the classical pathway begin with? a. Viruses b. Antigen-antibody complexes c. Mast cells d. Macrophages - B. Activation of the classical pathway begins only with the activation of protein C1 and is preceded by the formation of a complex ...

Viral infections can usually be treated with antibiotics. True or false? - False Antibody functions include all of the following except: A. targeting foreign cells so that complement proteins can cause cellular lysis B. linking soluble antigens together so that they fall out of solution C. binding and inactivating chemical toxins released by bacteria or other microorganisms D. cross-linking cell-bound antigens on red blood cells when blood types are properly matched - D. cross-linking ce...

SBB 5261 Exam 1 Final Questions and Answers 100% Verified IgG Sublcass most efficient in initiating classical complement - CORRECT ANSWERIgG3 Steric exclusion of water molecules is the mechanism of this enhancement - CORRECT ANSWER-PeG Stage of Complement activation common to all three pathways - CORRECT ANSWERActivation Phase-C3 convertase IgM agglutination is enhanced at what temperature - CORRECT ANSWER-Lower than RT Activation of C1 in classical pathway requires - CORRECT ANSWER...

An example of innate immunity is - ANSWER-NK cells Which of the following correctly describe innate immunity - ANSWER-Is always present in healthy individuals The body produces its own antibodies with which form of immunity - ANSWER-Active immunity Infection by a respiratory virus produces - ANSWER-Active immunity MALT is an example of a secondary lymphoid organ - ANSWER-True Both positive and negative selection can occur in the lymph nodes - ANSWER-False The functioning of the...

Lead poisoning affects the nervous system by A. Interfering with the function of neurotransmitters B. Inhibiting the production of myelin around nerves C. Increasing the resting membrane potential D. Altering the transport of potassium into the nerves - A Water movement between the intracellular fluid (ICF) compartment and the extracellular fluid (ECF) compartment is primarily a function of: A. Osmotic Forces B. Plasma Oncotic Pressure C. Antidiuretic hormone D. Hydrostatic forces - A ...

HUMORAL DEFENCES THE COMPLEMENT SYSTEM ANTIBODIES • Humoral immunity refers to the non cellular aspects of the immune system i.e. antibodies synthesis and the accessory processes that accompany it, including: • Th2 activation and cytokine production, • Germinal centre formation and isotype switching, • Affinity maturation and • Memory cell generation. • It also refers to the effector functions of antibody, which include: • Pathogen and toxin neutralization, • Classica...