Biochemistry C 785 Study notes 2022 (C785)

EPIGENETICS: Gene expression: making different proteins, increased expression makes protein and decreased expression stops making proteins ter- “start line” cription factors- protein that goes on top of the promoter “foot blocks” polymerase- enzyme that makes mRNA “runner” now knows where to go *1-3 turns gene on 4. nucleosomes- “on or off” big proteins that DNA wrap around, tightness depends on availability/exposes or hides promoters tight is decreased expression and loo...