cmls

Review Pathogenesis of Plasmodium falciparum malaria: the roles of parasite adhesion and antigenic variation Abstract. Malaria results in up to 2.5 million deaths an- nually, with young children and pregnant women at great- est risk. The great majority of severe disease is caused by Plasmodium falciparum. A characteristic feature of in- fection with P. falciparum is the accumulation or seques- tration of parasite-infected red blood cells (RBCs) in var- ious organs, such as the brain, lung...