ATI Skills module 2.0 Medication Administration 1 Notes
Duke University School Of Medicine
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ATI Skills module : Medication Administration
- Class notes • 20 pages • 2021
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B. Drug tolerance and dependence 
 Drug Tolerance to a drug develops as a patient’s physiological response 
to the medication decreases after repeated administration 
o Pts who have taken same meds or chemically related substance 
for period of time 
o Results in having to take higher doses to produce desired effect 
o Tolerance prone drugs: opioids, nitrates, benzodiazepines and 
barbiturates 
o Usually takes a month or longer to develop 
 Drug Dependence can be either psychologica...
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