MAT waiver

1. Dopamine release leads to subjective feelings of : pleasure, reward 2. Why would addiction be considered a disease?: Dz= a disorder of structure or function that produces specific signs or symptoms Addiction has defined causes (genetics, environment) and observable consequences (behavioral, biological) underlying change in brain circuits may persist beyond detoxification, particularly in individuals with severe disorders. (varies with drugs and intensity of use. Amphetamine may take a ye...

A 35-year-old man with opioid use disorder is being treated with 16mg of buprenorphine daily. He is abstinent from opioids, which has been confirmed by negative urine toxicology results, however his urines are intermittently positive for benzodiazepines and he notes drinking alcohol two days per week. Further history, corroborated by his wife, indicates that he drinks 2-4 beers, 2-3 days a week and feels intoxicated. He says he wants to stop drinking altogether and has tried, however hasn't bee...

continued medication tx vs medically supervised withdrawal - outcomes correct answer: continued med tx associated with better outcomes (TIP doesn't recommend med supervised short term withdrawal alone because of high rates of relapse) What makes less than daily dosing of buprenorphine possible? How would this dosing work? correct answer: long t1/2 (variable from 24-69 hours) and partial agonist properties along for less than daily dosing ex. doubling daily dose once stable and giving...

Dopamine release leads to subjective feelings of ______ correct answer: pleasure, reward Why would addiction be considered a disease? correct answer: Dz= a disorder of structure or function that produces specific signs or symptoms Addiction has defined causes (genetics, environment) and observable consequences (behavioral, biological) underlying change in brain circuits may persist beyond detoxification, particularly in individuals with severe disorders. (varies with drugs and ...

opioid mu receptor agonist drug effects: acute correct answer: euphoria, N&V, depressed respiration, sedation, analgesia, pruritus, miosis opioid mu receptor agonist drug effects: large dose acute correct answer: non-responsive, pinpoint pupils, anoxia/dilated pupils, bradycardia & hypotension, cyanotic, flacidity, pulm edema, slow or absent respiration opioid mu receptor agonist drug effects: chronic correct answer: dependence, withdrawal, tolerance, lethargy, constipation how does ...