Biochemistry USMLE Step 1
Liberty University
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USMLE FULL SOLUTION PACK STEP 1 AND STEP 2 Bundled exams with complete solution.
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A 73-year-old man comes to the office with fatigue that has become progressively
worse over the last several months. He is also short of breath when he walks up one
flight of stairs. He drinks 4 vodka martinis a day. He complains of numbness and tingling
in his feet. On physical examination he has decreased sensation of his feet. His
hematocrit is
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Biochemistry USMLE Step 1 questions and answers 2022/2023
- Exam (elaborations) • 22 pages • 2023
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Biochemistry USMLE Step 1 
Achondroplasia involves what defect? – 
Cell-signaling defect of fibroblast growth factor (FGF) receptor 3 
Marfan's syndrome involves a mutation in what? – 
Fibrillin gene 
Xanthine, hypoxanthine and uric acid are all what type of base? – 
Purine 
What is the rate limiting step in Purine de novo synthesis? – 
PRPP step via glutamin PRPP amidotranferase 
PRPP amidotransferase inhibited by what downstream products in 
purine synthesis? – 
IMP, GMP, AMP and pu...
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