NURS 421
University Of Louisiana At Lafayette
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NURS 421 - Exam 1 Study Guide.
- Exam (elaborations) • 77 pages • 2021
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NURS 421 - Exam 1 Study Guide/NURS 421 - Exam 1 Study Guide. 
 UNIT 1: Overview of Critical Care 
● Critical Care Specialty Units 
o Developed as a result of the recognition that patients with acute, life-threatening illness/injury could be 
managed more effectively if they were placed on specifically designated units. 
o History 
▪ Florence Nightingale described the advantages of placing patients recovering from surgery in 
separate areas (1800s).
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NURS 421 - Final Exam Study Guide.
- Exam (elaborations) • 25 pages • 2021
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NURS 421 - Final Exam Study Guide/NURS 421 - Final Exam Study Guide. 
Organ Transplants 
· Historically called “harvesting” but now is referred to as transplantation or procurement 
· Most commonly transplanted organs are… 
o Kidney, liver & heart 
o *Kidneys are #1 
o *Liver transplant problems indicated by prolonged PT 
· Other organs that may be transplanted include lungs, pancreas & small intestines 
· Other Donations: Corneas, Tissues, Hands and face, Blood stem cells, cord stem c...
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NURS 421 - Exam 3 Study Guide.
- Exam (elaborations) • 78 pages • 2021
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NURS 421 - Exam 3 Study Guide/NURS 421 - Exam 3 Study Guide. 
NCREASED INTRACRANIAL PRESSURE 
Pathophysiology 
· Skull encases 3 volume components (1. brain tissue (78%), 2. Blood (12%), & 3. CSF (10%) 
o Total volume of the components is 1900mL 
· Brain compromises…aka what the brain uses to function 
o 2% of body weight 
o 15-20% of CO 
o 20% of O2 consumption 
o 25% of glucose consumption 
o 90% of O2 consumed is used to generate ATP 
o “The brain needs a LOT of O2 and glucose when ...
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