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MSN 611 STATPEARLS EXAM 1 ACTUAL QUESTION AND ANSWERS LATEST 2023
Where are H4 receptors located? correct answer: predominantly found on eosinophils, neutrophils, and T cells. 
 
In the stomach, histamine is released by: correct answer: enterochromaffin-like (ECL) cells 
 
Toxic effect of first-generation antihistamines correct answer: cardiac arrhythmias 
 
Anaphylaxis and Antihistamine correct answer: Steroids may be added as adjunct therapy 
 
Central nervous system side effect of antihistamines that elderly patients should be aware of correct answer: ...
Which of the following is an FDA-approved indication for methotrexate? 
a. Wilms' tumor 
b. Breast cancer 
c. Colorectal cancer 
d. Multiple myeloma correct answer: b. Breast cancer 
 
In the stomach, histamine is released by: 
a. Parietal cells 
b. Enterochromaffin-like cells. 
c. Chief cells. 
d. Mucoid cells. correct answer: b. Enterochromaffin-like cells. 
 
Some first-generation antihistamines are used: 
 
a. to prevent motion sickness 
b. as anticonvulsants 
c. as laxatives. 
d. as stim...
1. What cells released histamine? correct answer: -Mast cells 
-ECL cells of the stomach 
 
1. Under what two circumstances may second-generation antihistamines cause drowsiness? correct answer: When combined with medications that cause CNS depression or alcohol 
 
1. Drugs typically used to treat the symptoms of an allergic reaction or allergic rhinitis? correct answer: -H1 Antihistamines 
 
1. Type of antihistamines used to inhibit the secretion of gastric acid in patients with gastrointest...
Where are T4 receptors located? correct answer: Eosinophils, neutrophils, T cells 
 
In the stomach, histamine is released by what? correct answer: Enterochromaffin-like cells (ECL) 
 
What is a toxic effect of first-generation antihistamines? correct answer: Convulsions, postural hotn, cardiac arrhythmias 
 
Anaphylaxis & antihistamines correct answer: Antihistamines alone are not a sufficient treatment for anaphylaxis - antihistamines and steroids are added as adjuvant treatments 
 
CNS si...
Histamine that is not found within mast cells functions as a(n): correct answer: Neurotransmitter 
 
Toxic effect of first-generation antihistamines correct answer: Cardiac Arrhythmias 
 
What class of medication is used as adjunct therapy for anaphylaxis. correct answer: Steriods 
 
Central nervous system side effect of antihistamines that elderly patients should be aware of correct answer: Effects coordination, fatigue and temporary cognitive impairment 
 
Indication of H2 antihistamines c...
Location of H4 receptors correct answer: eosinophils, neutrophils, and T cells. 
 
Second-generation antihistamine that cannot be removed by hemodialysis correct answer: Cetirizine hydrochloride (Zyrtec) 
 
Diagnosis of enterobiasis correct answer: Pinworm can be diagnosed by perianal swab using adhesive tape that is examined microscopically for eggs. 
 
Treatment modalities of tuberculosis correct answer: Regimens with anything less frequent than daily dosing require directly observed thera...
GABAs role in anxiety is? correct answer: Inhibitory 
GABA-A, GABA-B, GABA-C 
Benzodiazepines bind to gamma subunit. 
 
Anxiety Disorder Symptoms: correct answer: Anxiety 
Worry 
Panic attacks 
Phobic avoidance 
Compulsions 
Muscle tension 
irritability 
 
Major Depressive Disorder Symptoms: correct answer: Depressed mood 
Interest/pleasure 
Suicidality 
Appetite/weight 
Guilt 
 
Anxiety and major depressive disorder shared symptoms: correct answer: Sleep concentration 
Fatigue 
Arousal 
 
F...
Partial agonist 5-HT1 receptor. Leads to anxiolytic action. Effective with GAD but not other anxiety disorders. Antidepressant at high doses. Used to augment antidepressants. Dose is 2-3 x per day up to 60 mg. Side Effects are dizziness, headache, sedation, nervousness, nausea. correct answer: Buspar 
 
Histamine H1 receptor antagonist 
Anticholinergic effects 
Short term effects on anxiety/tension 
Little data on long-term anxiolytic effects 
Dosing: 50-100 mg 3-4 times/day 
Use lower doses in...
ADHD is noted for a trio of symptoms what are they? correct answer: inattention, hyperactivity, and impulsivity 
 
The prominent symptom of ADHD can also be described as what? correct answer: executive dysfunction 
 
Executive dysfunction is hypothetically linked to ineffective information processing where? correct answer: dorsolateral prefrontal cortex 
 
The symptoms of ADHD may occur because patients do not activate what is in response to cognitive tasks and problem-solving? correct answer...