NBME

What is the likelihood that a donor's HLA type will match a relative's? - 1:4 What cellular process does Bcl-2 regulate? - apoptosis Overexpression of Bcl-2 leads to? - cancer What is the MOA of rifampin? - Inhibits DNA-dependent RNA polymerase (inhibits RNA synthesis) What are the only two hormones released by the posterior pituitary? - 1. oxytocin 2. ADH Metoclopramide is a? - D2 receptor anatagonist What is the mnemonic for the autonomic innervation of the male sexual response? - "...

What can be associated with gastric cancer at the gastroesophageal junction? - H. pylori What is esophagitis with linear ulcers associated with? - CMV What is esophagitis with "punched-out" ulcers associated with? - HSV-1 What is esophagitis with white psuedomembrane? - Candida What leads to acetaminophen toxicity? - Reduced glutathione levels Why does reduced glutathione levels lead to acetaminophen toxicity? - Glutathione is not there to bind to glutathione, which leads to a build up o...

RSV is an RNA virus that enters the cell via a fusion protein - (which is the target of the prophylactic monoclonal antibody drug Palivizumab) Gram-positive rods in a diabetic foot wound (or a World War I soldier fighting in a trench) means - means Clostridium perfringens (the causative organism of gas gangrene). Crepitus means gas in the tissues, which is produced as a byproduct of its highly virulent alpha toxin Crepitus - means gas in the tissues, which is produced as a byproduct of its ...

A homeless man has a 3-month history of decreased a-peptide, generalized wasting, low grade fever , worsening cough productive of blood, mucopurulent sputum. He has a 3-year history of alcohol abuse. Xray films of the chest show consolidation and cavitary lesions in the apices of the lungs. Which of the following is most likely inflammatory and/or immune response in the lung? A. Endothelial cell proliferation, vascular budding, fibroblasts B. Epithelioid cells, multinucleate giant cells, c...