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PHPR 813 EXAMS BUNDLE |study Questions with Complete Solutions
PHPR 813 EXAMS BUNDLE |study Questions with Complete Solutions
[Montrer plus]PHPR 813 EXAMS BUNDLE |study Questions with Complete Solutions
[Montrer plus]Major Groups of Microorganisms 
- Bacteria (prokaryote) 
- Fungi (eukaryote) 
- Viruses 
- Protozoa (eukaryote) 
- Algae 
Major Groups of Microorganisms: Bacteria (prokaryote) 
Commensal bacteria 
Opportunistic bacteria 
Pathogenic bacteria
Aperçu 3 sur 18 pages
Ajouter au panierMajor Groups of Microorganisms 
- Bacteria (prokaryote) 
- Fungi (eukaryote) 
- Viruses 
- Protozoa (eukaryote) 
- Algae 
Major Groups of Microorganisms: Bacteria (prokaryote) 
Commensal bacteria 
Opportunistic bacteria 
Pathogenic bacteria
Malaria - Caused by Anopheles Sp. / Plasmodium spp. 
250 million annual cases 
- 1 million deaths 
1 in 5 childhood deaths in africa 
pregnant women are high risk of dying 
cannot donate blood for 3 months after travel, 3 years after living there 
parasitic infection 
Plasmodium falciparum - malaria...
Aperçu 2 sur 9 pages
Ajouter au panierMalaria - Caused by Anopheles Sp. / Plasmodium spp. 
250 million annual cases 
- 1 million deaths 
1 in 5 childhood deaths in africa 
pregnant women are high risk of dying 
cannot donate blood for 3 months after travel, 3 years after living there 
parasitic infection 
Plasmodium falciparum - malaria...
Do gram + or - cells have an outer-membrane? 
gram negative 
What component of a bacterial cell is made of peptidoglycan? 
cell wall 
Describe the order of membranes in bacterial cells? 
Capsule (all cells) 
Outer membrane (gram - only) 
Cell wall (peptidoglycan) 
Cytoplasmic membrane
Aperçu 3 sur 22 pages
Ajouter au panierDo gram + or - cells have an outer-membrane? 
gram negative 
What component of a bacterial cell is made of peptidoglycan? 
cell wall 
Describe the order of membranes in bacterial cells? 
Capsule (all cells) 
Outer membrane (gram - only) 
Cell wall (peptidoglycan) 
Cytoplasmic membrane
What are the 3 primary species that can be categorized as opportunistic fungi? 
- Candida 
- Aspergillus 
- Mucorales 
Which species of fungi is responsible for approximately 90% of opportunistic infections? 
Candida 
Which species of fungi is associated with causing opportunistic infections in indi...
Aperçu 2 sur 7 pages
Ajouter au panierWhat are the 3 primary species that can be categorized as opportunistic fungi? 
- Candida 
- Aspergillus 
- Mucorales 
Which species of fungi is responsible for approximately 90% of opportunistic infections? 
Candida 
Which species of fungi is associated with causing opportunistic infections in indi...
peptidoglycan made up of ______________ 
2 sugars 
- NAM and NAG are connected together 
- NAM has peptide side chain composed of 5 amino acids that coss-links 
Lipopolysaccharide 
component of the gram-negative outer cell membrane (also known as endotoxin - contributes 
to disease
Aperçu 2 sur 7 pages
Ajouter au panierpeptidoglycan made up of ______________ 
2 sugars 
- NAM and NAG are connected together 
- NAM has peptide side chain composed of 5 amino acids that coss-links 
Lipopolysaccharide 
component of the gram-negative outer cell membrane (also known as endotoxin - contributes 
to disease
Fungi - -Eukaryotes 
-have: nucleus, mitochondria, and endoplasmic reticulum 
-Differ from mammalian cells by: rigid cell wall, cell wall sterol is ergosterol rather than 
cholesterol 
Polymers that give the cell wall rigidity - Glucan and Chitin 
Fungal Cells: Chitin and Glucans: - -Responsible for...
Aperçu 4 sur 43 pages
Ajouter au panierFungi - -Eukaryotes 
-have: nucleus, mitochondria, and endoplasmic reticulum 
-Differ from mammalian cells by: rigid cell wall, cell wall sterol is ergosterol rather than 
cholesterol 
Polymers that give the cell wall rigidity - Glucan and Chitin 
Fungal Cells: Chitin and Glucans: - -Responsible for...
Are Mycobacterium gram positive or negative? How would you describe their shape? 
Gram positive bacilli (rods) 
Mycobacterium cell wall has high lipid content containing what? 
Mycolic acids and lipoarabinomannan 
Why is Mycobacterium hard to stain, and what stain must be used? 
-The wax like surfac...
Aperçu 2 sur 5 pages
Ajouter au panierAre Mycobacterium gram positive or negative? How would you describe their shape? 
Gram positive bacilli (rods) 
Mycobacterium cell wall has high lipid content containing what? 
Mycolic acids and lipoarabinomannan 
Why is Mycobacterium hard to stain, and what stain must be used? 
-The wax like surfac...
What are the different types of bacteria? - Commensal, opportunistic, pathogenic 
Bacteria are prokaryotes (have nucleus) 
What are the different kinds of fungi? - Yeast and mold 
Fungi are eukaryotes 
What are the different kinds of Protozoa? - Free-living and parasitic
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Ajouter au panierWhat are the different types of bacteria? - Commensal, opportunistic, pathogenic 
Bacteria are prokaryotes (have nucleus) 
What are the different kinds of fungi? - Yeast and mold 
Fungi are eukaryotes 
What are the different kinds of Protozoa? - Free-living and parasitic
Bacteria Structure 
Capsule, outer membrane (only in gram-negative bacteria), cell wall murein, cytoplasmic 
membrane, nucleus equivalent, plasmid, 70S ribosomes, depot substances (metaphosphates, 
glycogen), flagella, attachment pili 
Gram-Positive Bacteria 
Thick peptidoglycan membrane (cross-link...
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Ajouter au panierBacteria Structure 
Capsule, outer membrane (only in gram-negative bacteria), cell wall murein, cytoplasmic 
membrane, nucleus equivalent, plasmid, 70S ribosomes, depot substances (metaphosphates, 
glycogen), flagella, attachment pili 
Gram-Positive Bacteria 
Thick peptidoglycan membrane (cross-link...
What generation cephalosporin is ceftriaxone? 
third 
What properties enhance cefriaxone's efficacy? 
The ability to diffuse across porins and enhanced stability to beta-lactamase 
What types of streptococci are covered by ceftriaxone? 
S. pneumoniae and viridans streptococci
Aperçu 1 sur 3 pages
Ajouter au panierWhat generation cephalosporin is ceftriaxone? 
third 
What properties enhance cefriaxone's efficacy? 
The ability to diffuse across porins and enhanced stability to beta-lactamase 
What types of streptococci are covered by ceftriaxone? 
S. pneumoniae and viridans streptococci
What are bacterial nucleic acids 
DNA (forms a nucleoid) and Plasmids 
How many base pairs in bacterial DNA 
several million 
Roughly how many base pairs in plasmids 
~20,000 
What are the subunits in prokaryotic ribosomes 
50S and 30S = 70S sedimentation 
Which ribosomal subunit can help identify a...
Aperçu 3 sur 22 pages
Ajouter au panierWhat are bacterial nucleic acids 
DNA (forms a nucleoid) and Plasmids 
How many base pairs in bacterial DNA 
several million 
Roughly how many base pairs in plasmids 
~20,000 
What are the subunits in prokaryotic ribosomes 
50S and 30S = 70S sedimentation 
Which ribosomal subunit can help identify a...
Fungi 
How do Fungi differ from mammalian cells? 
- contain a rigid cell well 
- cell wall sterol is ergosterol rather than cholesterol 
What is responsible for the rigidity of fungal cells? 
- chitin 
- glucan (polymers of sugar)
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Ajouter au panierFungi 
How do Fungi differ from mammalian cells? 
- contain a rigid cell well 
- cell wall sterol is ergosterol rather than cholesterol 
What is responsible for the rigidity of fungal cells? 
- chitin 
- glucan (polymers of sugar)
PHPR 813 Study Questions with 100% Correct 
Verified Answers 
Is Mycobacterium gram positive or negative? 
gram positive (purple) 
Tell me something about Mycobacterium's cell wall 
it has a high lipid content (wax-like appearance) 
- mycolic acids 
- lipoarabinomannan 
Acid fast stain is used to d...
Aperçu 3 sur 26 pages
Ajouter au panierPHPR 813 Study Questions with 100% Correct 
Verified Answers 
Is Mycobacterium gram positive or negative? 
gram positive (purple) 
Tell me something about Mycobacterium's cell wall 
it has a high lipid content (wax-like appearance) 
- mycolic acids 
- lipoarabinomannan 
Acid fast stain is used to d...
What is the significance of Malaria? 
- common around the world, except the U.S 
- pregnant women are at high risk of dying from malaria and/or having complications 
- transported trough mosquitoes (Anopheles sp.) 
What was used to controlled Maleria in the US before 1950's? 
DDT (but was banned- c...
Aperçu 2 sur 6 pages
Ajouter au panierWhat is the significance of Malaria? 
- common around the world, except the U.S 
- pregnant women are at high risk of dying from malaria and/or having complications 
- transported trough mosquitoes (Anopheles sp.) 
What was used to controlled Maleria in the US before 1950's? 
DDT (but was banned- c...
staphylococcus (staining) 
gram positive 
staphylococcus (arrangement) 
chains or pairs 
staphylococcus (blood agar) 
hemolysis 
staphylococcus (surface atnigens) 
Lancefield Group 
staphylococcus (shape) 
cocci 
staphylococcus (catalase) 
positive
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Ajouter au panierstaphylococcus (staining) 
gram positive 
staphylococcus (arrangement) 
chains or pairs 
staphylococcus (blood agar) 
hemolysis 
staphylococcus (surface atnigens) 
Lancefield Group 
staphylococcus (shape) 
cocci 
staphylococcus (catalase) 
positive
What mosquito species carries malaria? 
Anopheles 
While mosquitos can be one route for malaria transmission, what is the other? 
Transfusion of contaminated blood products 
How long should you wait before donating blood after traveling to malaria endemic areas? 
3 months 
How long should you wait b...
Aperçu 2 sur 8 pages
Ajouter au panierWhat mosquito species carries malaria? 
Anopheles 
While mosquitos can be one route for malaria transmission, what is the other? 
Transfusion of contaminated blood products 
How long should you wait before donating blood after traveling to malaria endemic areas? 
3 months 
How long should you wait b...
Enterobacteriaceae gram stain 
Gram negative - rod shaped 
Enterobacteriaceae metabolism 
- facultative 
- oxidase negative 
What is the immune activator in enterobacteriaceae responsible for may signs and symptoms 
of inflammatory syndrome? 
the outer membrane
Aperçu 2 sur 6 pages
Ajouter au panierEnterobacteriaceae gram stain 
Gram negative - rod shaped 
Enterobacteriaceae metabolism 
- facultative 
- oxidase negative 
What is the immune activator in enterobacteriaceae responsible for may signs and symptoms 
of inflammatory syndrome? 
the outer membrane
How is varicella zoster transmitted? 
aerosolized droplets inhalation 
What percentage of acute morbidity in the U.S. is caused by respiratory disease? Of that what 
percentage is due to viruses? 
Respiratory diseases have been associated with 75- 80% of all acute morbidity in the United 
States wit...
Aperçu 2 sur 7 pages
Ajouter au panierHow is varicella zoster transmitted? 
aerosolized droplets inhalation 
What percentage of acute morbidity in the U.S. is caused by respiratory disease? Of that what 
percentage is due to viruses? 
Respiratory diseases have been associated with 75- 80% of all acute morbidity in the United 
States wit...
Ceftaroline drug class 
Cephalosporin 
Why is ceftaroline a treatment option for MRSA that is resistant to beta lactams? 
Ceftaroline has an R3 side chain that includes a 1,3, thiazole ring that enhances affinity for PBP 
2a.
Aperçu 1 sur 3 pages
Ajouter au panierCeftaroline drug class 
Cephalosporin 
Why is ceftaroline a treatment option for MRSA that is resistant to beta lactams? 
Ceftaroline has an R3 side chain that includes a 1,3, thiazole ring that enhances affinity for PBP 
2a.
Daptomycin drug class 
Lipopeptide 
How many amino acids make up daptomycin? 
13 
How many of the amino acids seen in daptomycin are arranged in a cyclic structure? 
10 
What antibiotic was used to synthesize the structure of daptomycin? 
vancomycin
Aperçu 2 sur 5 pages
Ajouter au panierDaptomycin drug class 
Lipopeptide 
How many amino acids make up daptomycin? 
13 
How many of the amino acids seen in daptomycin are arranged in a cyclic structure? 
10 
What antibiotic was used to synthesize the structure of daptomycin? 
vancomycin
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