Pharmokinetics - Study guides, Class notes & Summaries

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EDAPT – Pharmokinetics: Questions & Solutions

Click and drag each item to where it affects pharmacokinetics in the elderly. - ️️Absorption Decreased gastric pH, Slowed gastric emptying, Movement through the entire GI tract slowed, Blood flow to the GI tract decreased 40-50% Distribution Decreased percentage of total body water, Increased fat content as lean body mass decreases, Fewer protein binding sites, specifically albumin Metabolism Decreased levels of microsomal enzymes, Hepatic metabolism decreased because of less blood ...

EDAPT- pharmokinetics Exam Practice Questions and Answers Which step describes the biochemical alteration of a drug into an active or inactive metabolite? - ANSWER-metabolism What is pharmacokinetics? - ANSWER-What happens to the drug from the time is enters the body until it leaves Steps in the body - ANSWER-Absorption Distribution Metabolism Excretion Match the steps of how a drug moves through the body to their descriptions. - ANSWER-The elimination of a drug and any of its metabol...

What steps should the nurse take after a medication error? Correct Answer-fill out an incident report, this helps the nurse identify factors contributing to the error *this is NOT part of the patients hospital record How many generic names does a drug have? Correct Answer-one What does the pharmacologic class of the drug address? Correct Answer-How the drug works in the body, the mechanism of action *only one Is the generic name of a drug capitalized? Correct Answer-no, it is lowercas...

(PK) Pharmokinetics and (PD) Pharmodynamics. Very small in #'s 1st in Humans -is it consumable for humans? Phase 0 clinical trial True or false: the federal food, drug, and cosmetic act is United States, federal law enacted by Congress? True True or false: the FD&C act can be found in the US code, which contains all general in permanent US laws beginning at 21 U.S.C.301? True

Pharmokinetics what the body does to the drug (absorption, distribution, metabolism, excretion) Pharmacodynamics what the drug does to the body; mechanism of action Why do we administer drugs intramuscularly? For drugs with poor absorption (or no IV line) What routes bypasses the liver(portal circulation) initially? Rectal and sublingual What are the 4 steps of a Pharmacokinetic Study? Step 1 : dose animal or human Step 2: collect samples(blood,urine,stool,bile) at various timepoints S...

Which step describes the biochemical alteration of a drug into an active or inactive metabolite? - metabolism What is pharmacokinetics? - What happens to the drug from the time is enters the body until it leaves Steps in the body - Absorption Distribution Metabolism Excretion

Pharmacological Principles, Exam 1 || With Questions & 100% Correct Answers Pharmacological Principles, Exam 1 || With Questions & 100% Correct Answers What is the therapeutic objective of drugs? - ANSWER - Provide maximum benefit with minimal harm What are the four phases of pharmokinetics? - ANSWER - Absorption Distribution Metabolism Elimination Drug must be _________________ because cell membranes have a double layer of phospholipids - ANSWER - lipid soluble The four processe...

Mechanism of action - Understand expected pharmacological effect. Pharmokinetics - what the body does to the drug Volume of distribution Clearance Bioavailability Dosing Pharmacodynamics - what the drug does to the body Receptors, effectors Dose-response curves Agonist, partial agonist, antagonist, inverse agonist Signaling mechanisms Receptor regulation