Hmx genetics - Study guides, Class notes & Summaries

HMX GENETICS- ALL/158 QUESTIONS AND ANSWERS (A+)

HMX Genetics Exam Questions and Answers

Causes of chromosomal aberrations - errors in chromosome segregation (causes whole chromosome aneuploidy) and/or DNA damage repair (causes structural variation) Anneal - the ability of two complementary nucleic acids to align in an opposing orientation to allow the nucleotide bases of one strand to form hydrogen bonds with the nucleotide bases of the complementary strand; used in microarrays to bind DNA and show fluorescence Absolute risk - A person's chances of developing a disease or dis...

Identical by descent - Answer regions inherited from same version of maternal chromosome. Will span a disease causing variant (Genetic) Linkage - Answer tendency of 2 genomic loci (variants or alleles) near each other on same chromosome to be inherited together. Is not binary. Determined in part by distance between 2 loci on same chromosomes

HMX Genetics- ALL

HMX Genetics- ALL Questions and and answers

Single Nucleotide Variant (SNV) - ANS differences in DNA sequence. 46 chromosomes. >1% of population. Common complex traits bp in nucleus - ANS 6 billion Chromatin - ANS packaged DNA. Composed of DNA helix wound around histone proteins forming nucleosomes. 150 bp of DNA wound around each histone core Amino acid - ANS 20 different molecules used to build proteins. Coded by genes. Organic. Contains a Carboxyl (-COOH) and an Amino (-NH2) group Cent...

HMX Genetics- ALL Questions and and answers.

Nucleotide - ANS deoxyribose, a 5C sugar with a hydroxyl group on the 3' carbon and a phosphate group on the 5' carbon, and a nitrogen base attached to the 1' carbon Amino acid - ANS coded 5' to 3' (N terminus to C terminus) Central dogma - ANS describes the flow of information from DNA (genotype) to RNA (portable) to protein (phenotype) via transcription and translation Codon - ANS A specific sequence of three adjacent bases on a strand of DNA o...