Hboc - Study guides, Class notes & Summaries

HBOC correct answers breast, ovarian, prostate, melanoma Familial Adenomatous Polyposis correct answers CHRPE (congenital hypertrophy of the retinal pigment epithelium) Li-Fraumeni correct answers TP53 Early breast, sarcoma (osteo or soft tissue), brain, leukemia, **adrenocortical carcinoma, **choroid plexus carcinoma (childhood), fam hx childhood onset tumors Cowden correct answers Folliular Thyroid, Breast, uterine, macrocephaly, Lhermitte-Duclose disease (LDD)= cerebellar dysplastic...

HBOC Lectures Exam 1 Questions & Answers 2024 Describe the Myriad - BRCA situation and how that impacted genetic testing for HBOC genes. - ANSWER-Myriad discovered the BRCA genes and patented them so that other researchers and laboratories could not study/test for BRCA with payment and/or expressed consent to Myriad. In effect, Myriad had a monopoly on BRCA genes, and gene panels by other companies were incomplete without BRCA testing. So, instead of sending one patient sample to one la...

Hereditary Breast and Ovarian Cancer (HBOC) Review Exam Questions & Answers How much breast and ovarian cancer is hereditary? - ANSWER-5-10% for breast cancer 10% for ovarian cancer 15-20% of breast cancers are familial clusters Autosomal Dominant High penetrance Breast cancer genes/Conditions - ANSWER-HBOC: BRCA1 and 2 Li-Fraumeni Syndrome: TP53 Cowden Syndrome: PTEN PALB2 Associated Cancer syndromes Hereditary Diffuse Gastric Cancer: CDH1 Peutz Jaeger Syndrome: STK...

HBOC Exam Questions & Answers 2024

HBOC Exam Questions & Answers 2024

HBOC Genes and Inheritance correct answers - BRCA1, BRCA2 - Autosomal Dominant BRCA1 cancer risks correct answers Primarily breast, Ovarian, Male Breast, Prostate, Pancreatic BRCA2 cancer risk correct answers Breast, Ovarian, male breast, prostate, pancreatic, melanoma What ethnic population has an increased risk for HBOC And what is their carrier frequency correct answers Ashkenazi Jewish - 1:40 individuals carry one of three founder mutations Carney Complex Keystone Features co...

Genetic testing for hereditary breast and ovarian cancer syndrome (hboc) exams 2024

NSG 533 - Oncogenesis; Exam with Complete Solutions Inherited forms of cancer are __________ mutations are thought to account for approximately _______% of all adult cancers Correct answer germ line 5-10% Hereditary diffuse gastric cancer (HDGC) susceptibility syndrome involves germ line mutations in which gene? What does it encode? Correct answer CDH1 gene that encodes the protein E-cadherin Hereditary breast & ovarian cancer is more common in which ethnic group? Correct answer More...

HBOC Genes and Inheritance correct answers - BRCA1, BRCA2 - Autosomal Dominant BRCA1 cancer risks correct answers Primarily breast, Ovarian, Male Breast, Prostate, Pancreatic BRCA2 cancer risk correct answers Breast, Ovarian, male breast, prostate, pancreatic, melanoma What ethnic population has an increased risk for HBOC And what is their carrier frequency correct answers Ashkenazi Jewish - 1:40 individuals carry one of three founder mutations Carney Complex Keystone Features co...

HBOC correct answers breast, ovarian, prostate, melanoma Familial Adenomatous Polyposis correct answers CHRPE (congenital hypertrophy of the retinal pigment epithelium) Li-Fraumini correct answers early breast, sarcoma, brain, leukemia, adrenocortical, choroid plexus tumors (childhood), fam hx childhood onset tumors Cowden correct answers Folliular Thyroid, Breast, uterine, macrocephaly, Lhermitte-Duclose disease (LDD)= cerebellar dysplastic gangliocytoma Cowden correct answers Papil...