Caspases - Study guides, Class notes & Summaries

Test Bank for Huether and McCance's Understanding Pathophysiology, Canadian Edition, 2nd Edition by Kelly Power, Stephanie Zettel, , Mohamed Toufic El-Hussein Table of Contents PART ONE: BASIC CONCEPTS OF PATHOPHYSIOLOGY Unit 1: The Cell 1. Cellular Biology 2. Genes and Genetic Diseases 3. Epigenetics and Disease 4. Altered Cellular and Tissue Biology 5. Fluids and Electrolytes, Acids and Bases Unit 2: Mechanisms of Self-Defense 6. Innate Immunity: Inflammation and Wound Healing 7...

NBME PATHOLOGY EXAM WITH LATEST VERIFIED QUESTIONS AND 100% CORRECT ANSWERS GRADED A+ Apoptosis: - ANS-Programmed cell death. REQUIRES ATP. Can occur via the intrinsic or extrinsic pathways, both of which involve activation of cytosolic caspases which mediate cellular breakdown. ***Unlike necrosis, apoptosis does not involve significant inflammation. Involves eosinophilic cytoplasm, cell shrinkage, pyknosis and basophilia, membrane blebbing and karyorrhexis, and formation of apoptot...

NBME Pathology verified 100% full solution Apoptosis: - ANSWER-Programmed cell death. REQUIRES ATP. Can occur via the intrinsic or extrinsic pathways, both of which involve activation of cytosolic caspases which mediate cellular breakdown. ***Unlike necrosis, apoptosis does not involve significant inflammation. Involves eosinophilic cytoplasm, cell shrinkage, pyknosis and basophilia, membrane blebbing and karyorrhexis, and formation of apoptotic bodies which are phagocytosed. **DNA ladderin...

NSG5003 FINAL WEEK 10 QUIZ-QUESTIONS AND CORRECT ANSWERS Understanding the various steps of proteolytic cascades, such as caspase-mediated apoptosis and complement cascades, may be useful in designing drug therapy for which human diseases NSG5003 FINAL WEEK 10 QUIZ-QUESTIONS AND CORRECT ANSWERS Understanding the various steps of proteolytic cascades, such as caspase-mediated apoptosis and complement cascades, may be useful in designing drug therapy for which human diseases NSG5003 FINAL WEEK...

CBNS 150 FINAL TEST QUESTIONS & ANSWERS 2024/2025 What are the major players of apoptosis? - ANSWERS- Bax - Bcl2 - caspases - cytochrome c - APAF1 - Mitochondria Who is considered "guardian of the genome"? - ANSWERSp53 Why does p53+/+ cells have a lower percent survival after x-irradiation than p53-/- cells? - ANSWERSApoptosis is induced by WT p53 in response to DNA damage How many different types of cancer are there? - ANSWERSAbout as many as there are different types of c...

Bcl-2 ____ cell death - inhibits Bad, Bax and Bid _______ cell death - promote pro-apoptotic complexes insert into - outer mitochondrial membrane cytochrome c is usually in - the inner membrane space cytochrome c - moves electrons in electron transport chain cytochrome c binds ______ and _________ to form the ____________ - adaptor, caspases, apoptosome caspases - special kinds of proteases involved in cell death

19S - regulatory particle of proteasome 2 Categories of Epigenetics - DNA methylatioin and histone modification 20S - core particle of proteasome 26S proteasome - inhibited in sporadic parkinsonism 3 groups of Bcl-2 family proteins - 1. Group I - Anti-apoptitic 2. Group II - Inducers 3. Group III - Potentiate 3 key molecules of apoptosis - 1. Bcl-2 family proteins 2. Apaf-1 3. caspases 3 metabolic pathways that regulate aging - 1. Dietary restrictions 2. Insulin/Insulin-like Growth Fa...

MMSC490 Final Exam Questions with 100% Answers Humans possess about .............. different cell types. 100 200 500 1,000 - Answer️️ -200 In adult organisms, cell death must be balanced by cell growth. differentiation. renewal. migration. - Answer️️ -renewal The distinct series of changes that characterizes programmed cell death is called necrosis. apoptosis. sepsis. execution. - Answer️️ -apoptosis Cells that die as the result of acute injury undergo lysis. sepsis...

Insulin increases glucose transport into skeletal muscle cells by: - Increasing translocation of GLUT- 4-containing vesicles to the plasma membrane An inhibitor of the serine kinase GSK-3beta will have all of the following effects on insulin-resistant skeletal muscle except: - Cause decreased serine phosphorylation of IRS-1 in the presence of insulin. - Cause increased insulin-stimulated glucose transport. - Cause decreased insulin-stimulated tyrosine phosphorylation. - Cause reduced seri...

MMSC 490 Final Exam Questions with Correct Answers Humans possess about .............. different cell types. 100 200 500 1,000 - Answer-200 In adult organisms, cell death must be balanced by cell growth. differentiation. renewal. migration. - Answer-renewal The distinct series of changes that characterizes programmed cell death is called necrosis. apoptosis. sepsis. execution. - Answer-apoptosis Cells that die as the result of acute injury undergo lysis. sepsis. apoptosis. ...

Dysplasia - correct answer 1) Abnormal tissue growth 2) cells vary in size, shape & appearance Dysplasia ex - correct answer abnormal cells present in PAP smear of cervix (considered precancerous condition) Hyperplasia - correct answer 1) increase in number of cells of an organ/tissue (seen in epithelial & connective tissue only 2) muscle & nervous ...

MMSC490 Final Exam Questions with 100% Answers Humans possess about .............. different cell types. 100 200 500 1,000 - Answer️️ -200 In adult organisms, cell death must be balanced by cell growth. differentiation. renewal. migration. - Answer️️ -renewal The distinct series of changes that characterizes programmed cell death is called necrosis. apoptosis. sepsis. execution. - Answer️️ -apoptosis Cells that die as the result of acute injury undergo lysis. sepsis...