Competitive antagonist - Study guides, Class notes & Summaries

Pharmacology NMP Exam Questions & Answers 2024/2025 Pharmacokinetics - ANSWERSWhat the body does to the drug. It involves ADME Pharmacodynamics - ANSWERSWhat the drugs do to the body Receptor - ANSWERSA protein molecule in a cell membrane First Pass Metabolism - ANSWERSdrugs absorbed during pass through portal system at liver. this significantly reduces bioavailability and the amount of active drug that reaches the general circulation Enterohepatic Recirculation - ANSWERSWhen dr...

GMS 6504 MODULE 1-3 Exam 1 Questions With 100% Verified Answers What are System Independent Parameters? - answerAffinity Efficacy What are the parts of a system that are identified as System Dependent Parameters? - answerNumber of receptors Cellular machinery Presence of other drugs - Competitive - Noncompetitive Affinity is - answerThermokinetic propensity of drug to bind to receptor Based largely on ΔG Efficacy is - answerMagnitude of change of receptor shape/function upon drug bi...

Competitive Antagonists Compete with neurotransmitters for access to orthosteric binding sites on receptors *block responses to agonists How do competitive antagonists affect DRC? Cause a rightward shift How do you reverse the effects of a antagonists? Add more exogenous agonist or increase the concentration of endogenous for that receptor in order to overcome that antagonism When an antagonist competes with an agonist, does the antagonist always win and bind to orthos...

PHARMACOLOGY, TOXICOLOGY, PHARMACOKINETICS 1. Two dose-response curve response plotted on the same graph showed sigmoid curves having the same slope and height. T curve is located to the right of the A curve. Which of the following statements is/are correct regarding curves A an: I. A is more effective than B II. A is more potent than B III. A and B have the same ceiling dose IV. B is the graph produced when A is given with its competitive antagonist V. B is the graph produced when A is given wi...

PRE-NAPLEX EXAM Questions with 100% Correct Answers Cogentin (antiparkinson agent) benztropine 1 mg to 4 mg once or twice a day Blocks cholinergic histaminic receptors in the parasympathetic nervous system Mirapex (antiparkinson agent) Pramipexole 0.25 mg to 1.5 mg tid A non-ergot dopamine receptor agonist with a higher affinity to D3 dopamine receptors in the striatum and the substantia nigra Artane (Anti-parkinson agent) Trihexyphenidyl hcl 1 mg to 4 mg once or twice a day Bl...

PRE-NAPLEX EXAM Questions with 100% Correct Answers Cogentin (antiparkinson agent) benztropine 1 mg to 4 mg once or twice a day Blocks cholinergic histaminic receptors in the parasympathetic nervous system Mirapex (antiparkinson agent) Pramipexole 0.25 mg to 1.5 mg tid A non-ergot dopamine receptor agonist with a higher affinity to D3 dopamine receptors in the striatum and the substantia nigra Artane (Anti-parkinson agent) Trihexyphenidyl hcl 1 mg to 4 mg once or twice a day Bl...

A patient has asked you about the difference between a generic drug and a trade- or brand name drug. You explain that a generic drug (select all that apply) A. has the potential for abuse and dependence B. has the same chemical composition as the brand name drug. C. may have several brand names D. may have several generic names E. is usually less expensive than a brand-name drug - B. has the same chemical composition as the brand name drug. C. may have several brand names E. is usuall...

Pharmacodynamics Unit 1 Edapt Pharm A drug can compete with an agonist to deactivate a cell, which makes the drug a _______ ________ ️competitive antagonist A drug can deactivate with a cell or act as an _______ ️antagonist A drug can modify the effect of tissues or cells by activating a receptor or acting as an _______ ️agonist A drug that prevents a receptor or enzyme from activating is referred by which term? a. Agonist b. Partial agonist c. Antagonist d. Competit...

Which of the following is an up-regulation response in drug action? a. depolarization b. hyperpolarization c. increasing excitability of the neurons d. decrease receptor density. e. increase receptor density. - ANS E. Increase receptor density If a drug A mimics the effects of drug B completely, it is a a. full agonist. b. partial agonist. c. full antagonist. d. partial antagonist. e. inverse agonist. - ANS A. Full agonist If a drug A binds to the same binding sit...

NR565 EXAM REVIEW QUESTIONS AND ANSWERS 100% ACCURATE. VERIFIED/ Pharmacodynamics - -is the study of how drugs affect the body pharmacokinetics - -is the study of how the body affects the study of the way the body deals with the absorption, distribution, metabolism, and excretion of drugs under investigation expressed in mathematical terms. Absorption: - -Absorption is the process whereby a substance entering the body is assimilated by it. For proper pharmacokinetics study, it is nece...