Neuropsychopharmacology Exam 1 Questions And Answers
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Course
NEUROPSYCHOPHARMACOLOGY
Institution
NEUROPSYCHOPHARMACOLOGY
Which of the following is an up-regulation response in drug action?
a. depolarization
b. hyperpolarization
c. increasing excitability of the neurons
d. decrease receptor density.
e. increase receptor density. - ANS E. Increase receptor density
If a drug A mimics the effects of drug ...
Neuropsychopharmacology Exam 1
Questions And Answers
Which of the following is an up-regulation response in drug action?
a. depolarization
b. hyperpolarization
c. increasing excitability of the neurons
d. decrease receptor density.
e. increase receptor density. - ANS E. Increase receptor density
If a drug A mimics the effects of drug B completely, it is a
a. full agonist.
b. partial agonist.
c. full antagonist.
d. partial antagonist.
e. inverse agonist. - ANS A. Full agonist
If a drug A binds to the same binding site as drug B, the binding is
a. reversible.
b. irreversible.
c. competitive.
d. non-competitive.
e. permanent. - ANS C. competitive
If a drug A reverses the effect of drug B, it is a
a. full agonist.
b. partial agonist.
c. full antagonist.
d. partial antagonist.
e. inverse agonist. - ANS Reverse agonist
Affinity to a receptor is
a. Brownian motion of molecules.
b. attractiveness of molecules to the receptor binding site.
c. attraction of molecules to pretty receptors.
d. reversibility of binding of molecules to the binding site.
e. irreversibility of binding of molecules to the binding site. - ANS B. Attractiveness of
molecules to the receptor binding site
, Potency is a measure of
a. selectivity of drug binding to the binding site.
b. efficacy of drug onto the downstream neuron.
c. affinity of drug to receptor binding site.
d. amount of drug concentration to produce a drug effect. e. specificity of drug binding to the
binding site. - ANS D. Amount of drug concentration to produce a drug effect
Selectivity is a measure of
a. blockade of binding of a molecule to a binding site.
b. strength of binding of molecule to a binding site.
c. reversibility of binding of molecules to a binding site.
d. affinity of molecule to any receptor binding site indiscriminately.
e. selective binding of a molecule to a specific binding site but not any
other binding sites. - ANS E. Selective binding of a molecule to a specific binding site, but
not any other binding site
Natural neurotransmitters can bind to all of its receptor subtypes, and cannot distinguish the
difference among these receptor subtypes. What kind of binding does neurotransmitter bind to
these receptor subtypes?
a. Neurotransmitters are non-selective to the receptor subtype binding. b. Neurotransmitters are
selective to the receptor subtype binding.
c. Neurotransmitter bindings are reversible to these receptor subtypes. d. Neurotransmitter
bindings are irreversible to these receptor subtypes. e. Neurotransmitter bindings are
antagonists to these receptor subtypes. - ANS a
ValiumTM only binds to the benzodiazapine binding site of GABAA receptor, but not to GABAB
receptor. It means ValiumTM is
a. competitive to GABAA receptor.
b. non-competitive GABAA receptor.
c. selective to GABAA receptor.
d. non-selective to GABAA receptor.
e. antagonistic to GABAA receptor. - ANS b
If a drug A can displace the binding of drug B, the binding is
a. competitive.
b. non-competive. c. selective.
d. non-selective. e. reversible. - ANS A
NaloxoneTM blocks the opioid receptor. What type of drug is NaloxoneTM?
a. placebo.
b. inverse agonist.
c. agonist.
d. antagonist.
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