Bleomycin - Study guides, Class notes & Summaries

Time it takes for amount of drug to fall to half of its value, constant in first order kinetics (majority of drugs) correct answers Half-life (T1/2) Inducers of Cytochrome P450 (CYP450) (4) correct answers Barbiturates Phenytoin Carbamazepine Rifampin Inhibitors of CYP450 correct answers Cimetidine Ketoconazole Erythromycin Isoniazid Grapefruit Their MOA utilizes intracellular receptors: correct answers Thyroid and steroid hormones This compound's MOA utilizes transmembrane ...

Pleural Effusion - fluid in pleural space pneumothorax - air in the pleural space Which chemo has a high risk for pulmonary toxicity? - bleomycin (Blenoxane) For which pulmonary toxicity does bleomycin have a high risk? - Pneumonitis Hypocapnia - reduced carbon dioxide in the blood Signs and Symptoms of pleural effusion - tachypnea (fast breathing) decreased breath sounds dullness to percussion Define Lymphedema - obstruction of lymphatic system that caused overload of lymph in the inte...

Doxorubicin Cardiotoxic TISSUE VESICANT Baseline MUGA and total dose (CONCERN at 550 mg/m2) URINE=RED IF EXTRAVASATION OCCURS= cool/ice + Totect Idamycin Cardiotoxic (cardiomyopathy) Bleomycin AVOID oxygen supplementation Methotrexate Leukovorin decreases cytotoxicity Pemetrexed Vitamin B12 & folic acid supplements to decrease toxicity Fludarabine Immunosuppression Thioguanine Bone Marrow Suppression Stomatitis/Mucositis 5-FU *Stomati...

CPHON Examples of Alkylating Agents - correct answer Carboplatin, Cisplatin, Carmustine, Lomustine, Cytoxan, Ifosfamide, Melphalan, Temozolomide, Thiotepa Examples of Antimetabolites (Cell-cycle Specific) - correct answer MTX, 5-FU, ARA-C, 6-MP, 6-TG Examples of Plant Detrivatives (Cell-cycle Specific) - correct answer Etoposide, irinotecan, vincristine Examples of Antibiotics for Cancer treatment - correct answer Dactinomycin, Bleomycin Examples of Anthracyclines - correct answer D...

hypertension (HTN) correct answers persistently high blood pressure Initial drug therapy for newly diagnosed HTN correct answers thiazide diuretics (found to be the best out of the classes of diuretics) Thiazide diuretics (examples) correct answers -hydrochlorothiazide -chlorothiazide -hydroflumethiazide -methyclothiazide Diltiazem belongs to what drug class correct answers calcium channel blockers Adverse effects of diltiazem correct answers CNS-dizziness, lightheadedness, headac...

vesicants bleomycin, carmustine, cisplatin, daunorubicin, doxorubicin, etposide, idarubicin, melphalan, taxol, vincristine cisplatin antidote sodium thiosulfate doxorubicin antidote Dexrazoxane vincristine antidote hyaluronidase Alkylating agents busulfan, cytoxan, melphalan, ifosfamide, carmustine; cell cycle non-specific; affects heme, GI, reproductive antimetabolites methotrexate, 5-FU, cytarabine, gemcitabine, fludarabine; cell cycle specific, affect counts & GI platinum co...

Pleural Effusion fluid in pleural space pneumothorax air in the pleural space Which chemo has a high risk for pulmonary toxicity? bleomycin (Blenoxane) For which pulmonary toxicity does bleomycin have a high risk? Pneumonitis Hypocapnia reduced carbon dioxide in the blood

2024 Pharmacology HESI Exam Test Bank NCLEX-PN Guaranteed A+ Actual Questions and Answers, Complete 100% 1. Albuterol (Proventil HFA) two puffs and fluticasone propionate (Flovent Diskus) two puffs by metered-dose inhaler have been prescribed for a client with chronic obstructive pulmonary disease. The nurse caring for the client provides instructions regarding administration of the medication. Which statement by the client indicates an understanding of how to take these medications? 1...

Chemo Certification Practice Test 2024/2025 Questions and Answers 100% Solved Totect - Anecdote for Doxorubicin Warm Compress - Plant alkaloids and etoposide Bleomycin - bad for the lungs Leucovorin - potentiates the effects of 5-FU and decreases the effect of MTX Calvert Formula Components - Area under the curve (AUC) Carboplatin Creatinine Clearance Aromatase Inhibitors - used for postmenopausal women- osteoporosis Vesicant Administration - Prior to non-vesicant drugs Th...

Chemo Certification Practice Test 2024/2025 100% Solved | graded A Totect - Anecdote for Doxorubicin Warm Compress - Plant alkaloids and etoposide Bleomycin - bad for the lungs Leucovorin - potentiates the effects of 5-FU and decreases the effect of MTX Calvert Formula Components - Area under the curve (AUC) Carboplatin Creatinine Clearance Aromatase Inhibitors - used for postmenopausal women- osteoporosis Vesicant Administration - Prior to non-vesicant drugs Through a central line or...