Gms6504 exam 2 - Study guides, Class notes & Summaries

GMS6504 Exam 2 Questions And Correct Answers Graded A+...

GMS6504 Exam 2 Questions And Answers In terms of Lipinski's rules, which of the following functional groups serves as a hydrogen bond donor? ANS -NH2 Will a hydrophobic molecule have a high or low logP? ANS high Which is the best explanation as to why CNS drugs tend to have smaller polar surface areas than drugs that target things outside of the CNS? ANS It helps the drug cross the blood brain barrier Which functional group is most often utilized when making pro-drugs? ANS Ester...

GMS6504 #2 Exam Questions With Complete Solutions

GMS6504/GMS 6504 University Of Florida -GMS 6504 review exam 2 (P.S. 4-8) Questions With Complete Solutions

GMS6504 Exam 1&2 Advanced Med Pharm Verified Questions And Answers 2024/2025 Updates Which of the following would best be described as a system independent parameter determining pharmacological response? Receptor affinity for the ligand When taking a natural agonist and converting it to an antagonist using synthetic chemistry, what are the desired effects on affinity and efficacy? Affinity increases, efficacy decreases In the Langmuir equation, which variable represents the proportion of re...

GMS6504 Exam 2 Questions With Correct Answers What 4 factors determine whether a drug is good or bad? - answer1. Lipinski's Rule of 5 2. Chemical Reactivity: Good or bad 3. Functional Groups 4. Drug Targets Name atleast 3 Lipinski's Rules (Basic) - answer1. Molecular mass greater than 500 Da 2. High Lipophilicity, LogP greater than 5 3. More than 5H bond donors (FH,NH,OH) 4. More than 10H bond acceptors (O,F,N) When we have high values of Lipinski's Rules of 5. what does this tell u...