Carmustine - Study guides, Class notes & Summaries

Define neoadjuvant therapy - Answer Treatment is given prior to surgery to shrink the tumor Define adjuvant therapy - Answer Additional cancer treatment given after the primary treatment to lower the risk that the cancer reoccur 3 subcategories of alkylating agents: - Answer 1. Nitrogen mustards 2. Platinum-based agents (do not possess an alkyl group but still termed alkylating agents as they work similarly) 3. Nitrosoureas Common alkylating agents: - Answer Cyclophosphamide (...

the risk for significant bone marrow suppression (8) - Answer- advanced age (>65),poor nutritional status, preexisting autoimmune disease, DM, GI disorders, liver disease, or hematopoietic disease, and substance abuse. Cancer-induced bone marrow suppression (3) - Answer- a) dysfunctional hematopoietic cell within the bone marrow, b) bone marrow infiltration with tumor c)general exhaustion of bone marrow reserves solid tumor malignancies with the highest propensity to infiltrate the bone...

ONS CHEMO/BIO Exam With 100% Correct Answers 2023 Aklylating Agents -Cyclophosphamide -Cisplatin -Carboplatin -Oxaliplatin Cyclophosphamide (Cytoxan) Alkylating agent (cytotoxic antineoplastic) Kills rapidly growing cells by interrupting DNA/RNA synthesis Can cause bone marrow suppression, N/V, acute hemorrhagic cystitis*, alopecia Aggressive hydration pre and post infusion Cisplatin Vesicant Severe n/v Renal failure (hydration and electrolyte replacement) Ototoxicity,...

the risk for significant bone marrow suppression (8) - correct answer advanced age (>65),poor nutritional status, preexisting autoimmune disease, DM, GI disorders, liver disease, or hematopoietic disease, and substance abuse. Cancer-induced bone marrow suppression (3) - correct answer a) dysfunctional hematopoietic cell within the bone marrow, b) bone marrow infiltration with tumor c)general exhaustion of bone marrow reserves solid tumor malignancies with the highest propensity to inf...

ONS Chemotherapy Immunotherapy Certificate Exam (2023/ 2024 Update) Questions and Verified Answers|100% Correct- Grade A Q: How is relative dose intensity (RDI) calculated? Answer: By comparing the dose that the patient ACTUALLY received to the planned dose of the standard regimen Q: How do alkylating agents work? Answer: By causing a break in the DNA helix strand, interfering with DNA replication and causing cell death Q: 3 subcategories of alkylating agents: A...

Doxorubicin Cardiotoxic TISSUE VESICANT Baseline MUGA and total dose (CONCERN at 550 mg/m2) URINE=RED IF EXTRAVASATION OCCURS= cool/ice + Totect Idamycin Cardiotoxic (cardiomyopathy) Bleomycin AVOID oxygen supplementation Methotrexate Leukovorin decreases cytotoxicity Pemetrexed Vitamin B12 & folic acid supplements to decrease toxicity Fludarabine Immunosuppression Thioguanine Bone Marrow Suppression Stomatitis/Mucositis 5-FU *Stomati...

BMTCN Review Chapter 4 - Transplant Preparative Regimens, Cellular Infusion, Acute Complications, an Questions with complete solution 2023/2024TRANSPLANT PREP REGIMENS - correct answer Treatment leading up to transplant Acronyms: Ara-C BCNU BU Cy DLT SCT TBI - correct answer Cytarabine Carmustine Busulfan Cyclophosphamide Dose limiting toxicity DStem cell transplant Total body irradiation Induction chemotherapy - correct answer The first treatment given for a disease. It is of...

vesicants bleomycin, carmustine, cisplatin, daunorubicin, doxorubicin, etposide, idarubicin, melphalan, taxol, vincristine cisplatin antidote sodium thiosulfate doxorubicin antidote Dexrazoxane vincristine antidote hyaluronidase Alkylating agents busulfan, cytoxan, melphalan, ifosfamide, carmustine; cell cycle non-specific; affects heme, GI, reproductive antimetabolites methotrexate, 5-FU, cytarabine, gemcitabine, fludarabine; cell cycle specific, affect counts & GI platinum co...

CPHON Examples of Alkylating Agents - correct answer Carboplatin, Cisplatin, Carmustine, Lomustine, Cytoxan, Ifosfamide, Melphalan, Temozolomide, Thiotepa Examples of Antimetabolites (Cell-cycle Specific) - correct answer MTX, 5-FU, ARA-C, 6-MP, 6-TG Examples of Plant Detrivatives (Cell-cycle Specific) - correct answer Etoposide, irinotecan, vincristine Examples of Antibiotics for Cancer treatment - correct answer Dactinomycin, Bleomycin Examples of Anthracyclines - correct answer D...

ONS Chemotherapy Immunotherapy Certificate exam with 100% correct Answers 2023 3 major phases of cell division: - Correct Answer-Interphase Mitotic phase Cytokinesis 3 steps of interphase: - Correct Answer-First growth phase (G1) Synthesis phase (S phase) Second growth phase (G2) 4 phases of mitosis: - Correct Answer-Prophase Metaphase Anaphase Telophase Innate immunity: - Correct Answer-Non-specific response, either: 1. Barrier (skin, mucous membranes, flora of skin/gut) 2. Cellu...