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NR-565 Advanced Pharmacology Fundamentals (NR565)
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NR565 Week 1 Quiz
Basics of Pharmacology
State the three (3) most important characteristics of any drug.
Effectiveness, safety, and selectivity.
Is it possible to have a selective drug?
No. All medications have side effects.
Define the four phases of pharmacokinetics.
Absorption, distribution, metabolism, and excretion.
Define pharmacodynamics.
The nature and intensity of the response that the drug has on the body.
Name the three most important goals of pre-administration assessment.
Evaluate effects, identify high-risk patients, and assess for self-care.
What factors can predispose an individual to adverse reactions from drugs?
Allergies, pregnancy, age, genetics, & pathological disease (kidney or liver)
What measures help reduce adverse reactions of medication administration?
A thorough patient history to identify those who may be high-risk & education.
What type of research is required to assess drug therapies?
The randomized controlled trial is required for all new medications.
What is a "blinded" study?
Participants don't know if they belong to the control or experimental group.
Which Amendment strengthened drug regulation after the Thalidomide tragedy in Europe?
The Harris-Kefauver Amendment to the FDA and the Cosmetic Act of 1962.
What is the purpose of having a trade name (proprietary or brand name) for a drug?
Trade names are easy to recall and pronounce, and good for marketing purposes.
What is one of the problems with trade names?
Using two brand named drugs that have the same ingredient can lead to overdose.
Pharmacokinetics
Absorption:
Absorption is the process whereby a substance entering the body is assimilated by it. For proper
pharmacokinetics study, it is necessary to know both the rate and the extent to which the active
substance or therapeutic moiety are absorbed. They include substances intended to produce / not
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