QUIZ 3 NSG 555 NEURO MODULE 7 + HEM MODULE 8 QUESTIONS WITH COMPLETE VERIFIED ANSWERS GRADED A++
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Course
NSG 555
Institution
NSG 555
QUIZ 3 NSG 555 NEURO MODULE 7 + HEM MODULE 8 QUESTIONS WITH COMPLETE VERIFIED ANSWERS GRADED A++
ALS
lou gehrig's disease
incurable progressive muscle weakness and eventually death
affects upper motor neurons and lower motor neurons.
age 55-75 is typical onset
sporatic, 5-10% familial...
EMG+clinical abnormalities (s/s LMN degeneration by clinical, electrophys and
neuropath exam, s/s UMN by clinical exam, progression of motor syndrome within a
region)
riluzole
for ALS, improves survival
antiglutamate slows progression of ALS
, s/e: asthenia, dizzy, gi distress, low WBC, elevated liver enzymes (check labs first and
then q 3mos)
Edaravone
free radical scavenger to reduce oxidative stress: decreases functional decline so
reduces symptoms progression)
INFUSION daily X14 days, then 14 days off, then daily X 10 days, 14 off, then repeat
s/s: contusion from injection, HA, gait change
SSRI, SNRI for ALS
improve depression, anxiety, and sleep s/s
SARI (trazadone). can improve emotional lability. Benzos may also be used and may
help with spasticity and muscle cramps
anticholinergics for ALS
TCAs, glycopyrrolate, atropine
for sialorrhea (saliva increase), depression, anxiety, sleep and pain
other meds for ALS
ALS: muscle relaxants (tizanidine, baclofen), dextromethorphan/quinidine for emotional
lability
modafinil--stimulant for fatigue
oxybutynin--bladder spasms
Bells Palsy
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