Exam (elaborations)
ADVANCED BIOCHEMISTRY FINAL EXAM QUESTIONS AND ANSWERS
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ADVANCED BIOCHEMISTRY FINAL EXAM QUESTIONS AND ANSWERS....
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N5, N10-methylene-THF - ANSWER directly used to convert uracils tothymines
5-methyl uracil - ANSWER N5,N10-methylene-THF methylates where
N5-methyl-THF - ANSWER used to remethylate homocysteine
folic acid - ANSWER the typical nature of the supplement found in USA wheat
flour to provide methylated forms of THF.
DHF - ANSWER normal substrate for the enzyme inhibited by methotrexate
(an early chemotherapeutic agent).
Trimethoprim - ANSWER inhibitor of DHF reductase found in a widely
distributed "sulfa drug"
Acyclovir - ANSWER toxic agent avidly activated by herpes thymine kinase
Replication - ANSWER what process does acyclovir inhibit
Doxyclycline - ANSWER inhibitor of A site occupancy by aminoacyl-tRNAs?
concentrated - ANSWER Doxycline affects bacteria because it is?
increases Uracils in DNA because you cannot change from Uracils to Thymines
which will ultimately cause apoptosis due to too much gaps in the DNA -
ANSWER lack of folic acid
Takes the Uracils out of the DNA in order for repair endonuclease to "fix" the
DNA - ANSWER Uracil DNA glycosylase
activates apoptosis - ANSWER double-strand and single- strand breaks in
DNA caused by damage
, activates expression of Nox2 which produces O radicals which activate s-
nitrosohomocysteine - ANSWER homocysteine activates?
Glutathione - ANSWER cysteine is important in making
rrpsy - ANSWER recognition sequence for pka
bZIP proteins - ANSWER Basic and Leucine zipper (CREB)
CREB - ANSWER cAMP response element binding protein
transcription factor
histone acetyltransferase (HAT) - ANSWER unwraps the DNA (acetylation)
CARM1/PRMT - ANSWER Methylates CBP
Flavin - ANSWER
Ribose - ANSWER What is flavin attached to?
Histidine - ANSWER Imidazole that flavin is attached to
Guanine - ANSWER
G-cap - ANSWER modification of guanine
Adenine - ANSWER
Nicotinamide - ANSWER
Thymine - ANSWER
Cytosine - ANSWER
Uracil - ANSWER
1 - ANSWER Which numbered atom bonds to the 1' carbon of ribose?
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