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NSG 552 PSYCHOPHARMACOLOGY EXAM – QUESTIONS WITH COMPLETE SOLUTIONS
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NSG 552 PSYCHOPHARMACOLOGY EXAM – QUESTIONS WITH COMPLETE SOLUTIONS
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NSG 552 PSYCHOPHARMACOLOGY EXAM – QUESTIONSWITH COMPLETE SOLUTIONS
The study of the use of psychotropic medications in the treatment of
psychiatric disorders: Right Ans - Psychopharmacology
The study of what the body does to drugs: Right Ans - Pharmacokinetics
The study of what the drugs does to the body: Right Ans -
Pharmacodynamics
Involves the absorption, distribution, metabolism and excretion of meds:
Right Ans - First Pass Metabolism (C.Y.P. 450)
Increase serum levels of other drugs that are substrates of that enzyme:
Right Ans - Enzyme inhibitors will slow down metabolism causing toxic levels
Decreases serum levels of other drugs that are substrates of that enzyme:
Right Ans - Enzyme inducers cause fast metabolism and create subtherapeutic
drug levels
Part of the brain that regulates powerful emotions such as fear, rage, sexual
desires: Right Ans - Amygdala
The relay station for sensory information: Right Ans - Thalamus
Essential for maintaining homeostasis, controls basic needs such as sleep-
wake cycles: Right Ans - Hypothalamus
This lobe is involved in executive functioning, high order planning, speech and
motivation: Right Ans - Frontal Lobe/ Prefrontal cortex
Derived from Tryptophan and made in the Ralphe Nuclei: Right Ans -
Serotonin
Made in the Locus Ceruleus and involved in the noradrenergic pathways:
Right Ans - Norepinephrine
, 90% of serotonin receptors are found in the: Right Ans - GI tract
Produced in the V.T.A. (Reward Pathway) and involved in the four major
pathways: Right Ans - Dopamine
Dopamine inhibits prolactin in this pathway: Right Ans -
Tuberoinfundibular
Increase dopamine in this pathway is associated with positive symptoms:
Right Ans - Mesolimbic Pathway
Decrease dopamine in this pathway is associated with negative symptoms:
Right Ans - Mesocortical Pathway
Decrease dopamine in this pathway produces motor symptoms: Right Ans -
Nigrostriatal Pathway
Main inhibitory neurotransmitter that induces calmness and relaxation:
Right Ans - Gamma- aminobutyric acid (GABA), Off switch
Main excitatory neurotransmitter: Right Ans - Glutamate, On Switch
Major organ that breaks down drugs in the body: Right Ans - Liver
Electrolyte imbalance commonly associated with psychotropic medication
use: Right Ans - Hyponatremia
The time needed to clear 50% if drugs from the plasma: Right Ans - Half-
life
The process of becoming desensitized and less responsive to a particular
medication dose overtime necessitating an increase: Right Ans - Tolerance
A ration describing toxic dose to effective dose: Right Ans - Therapeutic
Index
A chemical that binds to a receptor to produce a biologic response: Right
Ans - Agonist
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