BIOL 4100 Auburn University Exam 2 Review (Dr. Flores &
Dr. Petrov) Questions With Complete Solutions
_________________ are normally found in
the bloodstream and are the most
abundant type of phagocyte,
constituting 50% to 60% of the
total circulating white blood cells Correct Answers
Neutrophils
__________________ will trigger the secretion of the ER
resident protein Correct Answers Mutations
____________________ provides the
energy to bring the two bilayers close
enough to destabilize them and fuse Correct Answers SNARE-
SNARE pairing
"professional
phagocytes" Correct Answers macrophages,
neutrophils and dentri5c
cells
remove microorganisms from infected tissues, and macrophages
eliminate aged or dead cells from tissues throughout the
body
Addition of a fatty acid by N-myristoylation: Correct Answers
Starts with the removal of an initiating methionine from the N-
terminus of a polypeptide chain. Next comes the myristoylation
,of on N-terminal glycine. Attachment is through an amide
covalent bond
After translocation across the outer
membrane, the proteins with multiple transmembrane domains
are bound by ____________
chaperones, which bring them to ___________ . The
protein is transferred laterally into the inner
membrane of the mitochondria Correct Answers Tim9-Tim10;
Tim22
Almost all the mitochondria of
fertilized eggs are contributed by
the ____, so germ-line mutations
are transmitted to the next
generation by the ______. Correct Answers ovum; mother
Attachment of myristoyl or prenyl groups can also: Correct
Answers promote intra- and intermolecular
protein:protein interactions.
Because of the _________________ structure of mitochondria,
import of
proteins is complex Correct Answers double-membrane
Calnexin (or calreticulin) Correct Answers recognizes the
glycoprotein and removes a glucose
Calnexin and Calreticulin Pathway Correct Answers Quality
Control in the ER
, Caveolae-Mediated Endocytosis is characterized by: Correct
Answers the presence of the membrane protein caveolin dimer,
essential to initiate the biogenesis of the caveolae
Caveolin are part of the __________________ Correct Answers
lipid rafts (subset)
cisternal maturation model Correct Answers proteins are
carried within the cisternae, which gradually mature and
progressively move through the Golgi in the cis to trans
direction
Clathrin-and caveolae- independent endocytosis Correct
Answers Cellular entry occurs in cells devoid of both clathrin
and caveolae
Clathrin-and caveolae- independent endocytosis can be observed
by using: Correct Answers Inhibitors of clathrin and caveolae
+ confocal microscopy + Cargo with a fluorescent tag
Clathrin-coated vesicles Correct Answers transport in both
directions
between the trans Golgi network,
endosomes, lysosomes, and
plasma membrane
Clathrin-mediated endocytosis Correct Answers The selective
uptake of specific macromolecules by receptors that concentrate
in clathrin-coated pits.
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