Exam (elaborations)
UNE Biochemistry Unit 1 Exam Questions and Answers
- Course
- Institution
UNE Biochemistry Unit 1 Exam Questions and Answers
[Show more]
Content preview
UNE Biochemistry Unit 1 ExamQuestions and Answers
What is primary structure of a protein? - Answers -Linear sequence of amino acids in a
polypeptide chain written from the N-terminus to the C-terminus.
What kind of structure contains a-helices and B-pleated sheets? - Answers -Secondary
structure
How are a-helices formed? - Answers -The CARBONYL group of a peptide bond forms
a HYDROGEN bond with the AMIDE nitrogen of another peptide bond FOUR amino
acids down the chain.
Are a-helices weak and loose or compact and rigid? - Answers -Compact and rigid
a-helices comprise what fraction of secondary structures? - Answers -About 1/3
Which amino acid can cause a kink in a-helices and is therefore not typically found in
them? - Answers -Proline
How are B-pleated sheets formed? - Answers -B strands are connected laterally by at
least two or three hydrogen backbone bonds.
B-pleated sheets are formed laterally between which groups on either B strand? -
Answers -C=O groups and NH groups
In which directions do R groups on B pleated sheets always protrude? - Answers -Up or
down.
If the B-pleated sheet has a hydrophobic side, where is it? - Answers -Buried in the
protein and will rarely be exposed to the polar H2O solvent.
If the B-pleated sheet has a hydrophilic side, where is it? - Answers -On the surface of
the protein and exposed to the polar H2O solvent.
What are bends/turns/loops? - Answers -Shorts stretches of the polypeptide chain that
are stabilized by hydrogen bonds and are NOT random
What is tertiary protein structure? - Answers -The total 3D conformation of the
polypeptide chain including interactions between a-helices, B-pleated sheets and any
loops/turns/bends
, The Rossman fold is an example of what type of structure? - Answers -Tertiary
What is a structural domain? - Answers -A section of protein sufficient to perform a
chemical or physical task. They are DEFINED regions with CONSERVED function.
What is a motif? - Answers -Common arrangement of secondary structures to form a
tertiary arrangement
What is quaternary structure? - Answers -A combination of two or more tertiary subunits
that work as one functioning unit.
What are similarities between myoglobin and hemoglobin? - Answers -They are
homologous. They have similar primary sequences. They both bind oxygen.
What is the function of hemoglobin? - Answers -Travels through the blood inside a red
blood cell in order to deliver oxygen form the lungs to the tissues
What is the function of myoglobin? - Answers -Remains in the heart and the skeletal
muscles in order to bind oxygen that is released by hemoglobin.
What is an apoprotein missing? - Answers -Its ligand. An example is hemoglobin if it
were missing heme.
What is a holoprotein? - Answers -A protein that has its ligand so that it is able to
function.
What is the general structure of myoglobin? - Answers -It is a monomer that has 8 a-
helices bound together by alpha turns.
Myoglobin has a ?? pocket that contains ?? and ?? at its center so that oxygen may
bind. - Answers -hydrophobic pocket, contains heme and fe2+
What is the fe2+ in myoglobin always bound to and what is the purpose of this binding?
- Answers -It is always bound to the histidine R group of the a-helix and this helps to
stabilize
What is heme tightly bound to and what is it considered? - Answers -The globin, a
prosthetic group
When represented on a graph, what kind of binding curve does myoglobin have? -
Answers -Hyperbolic
What is the general structure of hemoglobin? - Answers -It is a heterotetramer (four
subunits, one is different from the others). It has 2 a-helix and 2 B-pleated sheet
subunits. Each has its own heme.
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller millyphilip. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $12.49. You're not tied to anything after your purchase.
Can Stuvia be trusted?
4.6 stars on Google & Trustpilot (+1000 reviews)
67096 documents were sold in the last 30 days
Founded in 2010, the go-to place to buy study notes for 14 years now