Exam (elaborations)
Final Exam Review UNE medical biochemistry Exam Questions and Answers
- Course
- Institution
Final Exam Review UNE medical biochemistry Exam Questions and Answers
[Show more]
Content preview
Final Exam Review UNE medicalbiochemistry Exam Questions and
Answers
Under fasting conditions (ratio of insulin: glucagon <1), elevated glucagon will activate
which of the following enzymes? - Answers -hormone sensitive lipase
Ketonuria, hypoglycemia, and severe acidosis are prime diagnostic indicators of the
presentation of type 1 diabetic ketoacidosis. Which of the following compounds are
"ketone bodies" that would be elevated in serum of urine of a patient in this condition? -
Answers -D-3-hydroxybutyrate and acetoacetate
What is the purpose of cholesterol esterification within the cell? (the conversion of
cholesterol to cholesteryl ester)
a. this modification makes cholesterol more soluble in the plasma membrane
b. this modification does not change the chemical properties of cholesterol
c. esterification is the first step in the synthesis of cortisol
d. esterification traps cholesterol in the cell - Answers -esterification traps cholesterol in
the cell
An individual goes to bed around 8 pm and doesn't wake up until 9 am the next
morning. During this time, which of the following is the primary oxidizable substrate in
the skeletal muscle?
a. free fatty acids
b. glycogen
c. amino acids
d. lactate - Answers -free fatty acids
A 22-year-old woman engaging in a political protest goes on a hunger strike on a
prominent corner in a city park. She refuses all offers of food for except for water
through the first 2 weeks. Under these conditions there is a decreased reliance on
which of the following pathways for fuel?
a. β-oxidation
b. ketogenesis
c. gluconeogenesis
d. lipolysis - Answers -gluconeogenesis
In reverse cholesterol transport HDL interacts with the ABCA1 transporter to move
cholesterol from the cell to the HDL. This also requires the activity of which of the
following enzyme?
, a. lipoprotein lipase
b. cholesteryl ester transfer protein (CETP)
c. lecithin cholesterol acyltransferase (LCAT)
d. LDL receptor - Answers -lecithin cholesterol acyltransferase (LCAT)
A 16-year-old woman presents to her primary care physician for a follow up visit. At her
initial visit, 3 months ago, her serum cholesterol was 255 mg/dL (above normal). She
finds this very disappointing as she started a strict dietary regime reducing all fats and
cholesterol, replacing them with a high carbohydrate diet. You tell her that high
carbohydrate diets can increase serum triglyceride levels in some individuals. This can
be attributed in an increase in the synthesis of which of the following lipoproteins?
a. chylomicrons
b. VLDL
c. IDL
d. HDL
e. LDL - Answers -VLDL
a 5-year-old presents to her primary care physician. Her mother is concerned due to
persistent diarrhea which is worse when eating fatty foods. The child also has some
clinical signs of a deficiency in fat-soluble vitamins. Based on this information the child
likely has a deficiency in the ability to synthesize which of the following lipoproteins?
a. chylomicrons
b. VLDLs
c. LDLs
d. HDLs - Answers -chylomicrons
The interaction of chylomicorns with lipoprotein lipase is stimulated by which of the
following Apo proteins?
a. ApoB 100
b. Apo B 48
c. Apo C II
d. Apo E - Answers -Apo C II
A defect in the thioesterase subunit of fatty acid synthase would impair which of the
following activities of the enzyme complex?
a. liberation of newly assembled palmitate from the enzyme
b. priming of the enzyme iwth acetyl-CoA
c. Liberation of Co2 from 3-ketoacyl synthase
d. binding of malonyl-CoA to an SH group - Answers -liberation of newly assembled
palmitate from the enzyme
An increase in the ratio of insulin to glucagon leads to which of the following metabolic
shifts?
a. acetyl-CoA carboxylase will become dephosphorylated and active
b. cytosolic levels of malonyl-CoA will decrease
c. hormone sensitive lipase will become dephosphorylated and active
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller millyphilip. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $10.99. You're not tied to anything after your purchase.
Can Stuvia be trusted?
4.6 stars on Google & Trustpilot (+1000 reviews)
67096 documents were sold in the last 30 days
Founded in 2010, the go-to place to buy study notes for 14 years now