AD HAAD PHARMACY EXAM: SABEER NASRI
DOC | 100 QUESTIONS | WITH CORRECTLY
ANSWERED SOLUTIONS!!
Long case of Afro-Caribbean patient. He had severe ankle swelling. Which of
the following drug cause this condition
a. Nifedipine
b. Losartan
c. Metoprolol
d. spiranolacon Answer - Nifedipine
Lexicomp: Cardiovascular: Flushing (IR: 25%; ER: <3%), peripheral edema (4% to
30%).
google: Some swelling of the feet and ankles occurs in almost half the people
who take calcium channel blockers
which condition nasal spray of steroid is contraindicated
a. deviated septum
b. post nasal surgery
c. rhinitis
d. nasal infection Answer - post nasal surgery
Which drug can cause agranulocytosis:
a. Levothyroxine
b. Pyrimethamine
,c. .......
d. ......
(Cytarabin not in my option) Answer - Pyrimethamine
Found Facts:
- A serious condition that occurs when there is an extremely low number of
granulocytes (a type of white blood cell) in the blood.
-A variety of drugs can cause acquired agranulocytosis and neutropenia by
destroying special cells in the bone marrow that later mature and become
granulocytes (precursors). These drugs include phenytoin, pyrimethamine,
methotrexate, and cytarabine.
-Pyrimethamine, sold under the brand name Daraprim among others, is a
medication used with leucovorin to treat the parasitic diseases toxoplasmosis
and cystoisosporiasis. It is also used with dapsone as a second-line option to
prevent Pneumocystis jiroveci pneumonia in people with HIV/AIDS.
- Cytarabine (Conventional) (Lexi-Drugs):Antineoplastic Agent, Antimetabolite;
Antineoplastic Agent, Antimetabolite (Pyrimidine Analog)
-The following are the medications commonly involved with agranulocytosis:
Cancer chemotherapies.
Analgesic and anti-inflammatory (gold, naproxen, and penicillamine)
Anti-thyroid (carbimazole, propylthiouracil)[2][3]
Anti-arrhythmics (quinidine, procainamide)
Anti-hypertensives (captopril, enalapril, nifedipine)
Mother came with child having symptoms (nausea & vomiting blood). Test
results showed he had metabolic acidosis. Which of the following is the cause:
a. Acetaminophen
b. Aspirin
c. Iron
d. Ascorbic acid Answer - b. Aspirin
, -Aspirin causes high anion gap metabolic acidosis and respiratory alkalosis. The
high anion gap comes from the addition of salicylic acid as well as the
generation of lactic acid (due to uncoupling of oxidative phosphorylation
causing anaerobic respiration
-Lexicomp: Endocrine & metabolic: Dehydration, hyperglycemia, hyperkalemia,
hypoglycemia (children), increased thirst, metabolic acidosis
Patient using hyaluronate ophthalmic drug for 5 months now. Its expiration
date is on December 25th. what you will advise the patient:
a. Discard since it is opened for 28 days
b. Continue using since it did not complete 6 months and it is not expired
c. Discard although it is not expired Answer - Given answer: Continue using
since it did not complete 6 months and it is not expired
Found facts:
-HYLO-FORTE® Preservative Free and Phosphate Free
can be used for 6 months after opening. The bottle must be discarded after 6
months use.
-Composition: 1 ml HYLO-FORTE® contains 2 mg sodium hyaluronate, citric acid
anhydrous, sodium citrate, sorbitol and water for injections.
-What is HYLO-FORTE® used for? HYLO-FORTE® is an eye drop for the intensive
and therapeutic lubrication of the ocular surface in more severe and persistent
dry eye sensation including treatment after surgical procedures
-How long can you use eye drops after opening them? Many manufacturers
recommend that you throw away eye drops 28 days after opening the bottle.
This is because the preservatives inside can start to break down and allow
bacteria to grow.
Patient taking nitroglycerin mononitrate 60 mg XR once daily. He was under
control until he started to have symptoms. He decided to take another dose.
What is your appropriate action:
a. Ask physician to change to dinitrate since it has longer duration of action.
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