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MN 553 PHARMACOLOGY FINAL EXAM REVIEW QUESTIONS WITH CORRECT ANSWERS.
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MN 553 PHARMACOLOGY FINAL EXAM REVIEW QUESTIONS WITH CORRECT ANSWERS.
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MN553 PHARMACOLOGY FINAL EXAM REVIEWQUESTIONS WITH CORRECT ANSWERS
regulations - ANSWER -∙all states have title protection for NPs
•the board of nursing regulates practice
-5 states have joint oversight with medical board
•scope of practice is determined by NP license
investigational new drug (IND) - ANSWER -•required before an investigational
drug or bio product can be administered to a human
•the IND app is a compilation of all known information about the compound
•it also includes a description of the clinical research plan for the product
•specific protocol for phase I study
phases of clinical study - ANSWER -•phase I clinical eval is the 1st testing of a new
compound in subjects for the purpose of establishing the tolerance of healthy
human subjects
•phase II clinical eval is controlled studies performed on pts having the target
disease or disorder to determine a compound's potential usefulness and short
term risks
•phase III trials are controlled and uncontrolled clinical trials of a drug's safety
and efficacy in hospital and outpt settings
•phase III trials verify that the acceptable risk/benefit ratio seen in II persists
under conditions of anticipated usage in groups of pts large enough to identify
statistically and clinically significant responses
clinical judgment in prescribing - ANSWER -•is there clear indication for drug?
mn 553 Pharmacology final exam review QUESTIONS WITH CORRECT ANSWERS
,•what drugs are effective for the disease?
•what are the goals of therapy?
•monitoring to see if drug is meeting goals
•duplications in med pts is taking
•otc vs prescription
•cost
•sources of info
the process of prescribing - ANSWER -•identify the pts problem
•specify the therapeutic objective
•collab with the pt
•choose the treatment
•edu the pt
•mt for effectiveness
•individualize drug choice
special population: pregnancy - ANSWER -•avoid ACEI, consider BB
•bulk laxative
special population: nursing moms - ANSWER -avoid ACEI, consider BB
special population: pediatric - ANSWER -•best pharmaceuticals for children act
(BPCA)
•authorizes research to promote efficacy and safety
mn 553 Pharmacology final exam review QUESTIONS WITH CORRECT ANSWERS
, special population: older adults - ANSWER -•beers criteria
-looks at potential risk
-does not look at effectiveness
pediatric distribution - ANSWER -•newborns and infants have higher percentage
of water
•BBB is incomplete and permeable in newborn
•infants younger than 6 mths of age have decreased plasma proteins available for
drug binding
•in infants dosing needs to be decreased if metabolized by kidneys
older adults - ANSWER -•take more meds than any other age group
•PD and PK are altered
•ADRs common
•risk increase with number of drugs used
•decreased protein impacts absorption
medication metabolisms - ANSWER -•some meds need a loading dose
first pass - ANSWER -occurs when metabolized by the liver
peak levels - ANSWER -important to have this to achieve desired effect
half-life - ANSWER -•ibuprofen ~2 hours
•SSRI~ 22 hours
mn 553 Pharmacology final exam review QUESTIONS WITH CORRECT ANSWERS
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