Neuropsychopharmacology Exam 1 Questions And Answers
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Course
NEUROPSYCHOPHARMACOLOGY
Institution
NEUROPSYCHOPHARMACOLOGY
Receptor-binding process - ANS alters the cell's function
NT/hormone
Binds w/ receptor
Send signal to alter biological functions
Signal transduction
Transduce (convert) signal from outside to the inside of cell
ACh(neurotransmitter) - ANS Subtype: naCH receptor
Localization...
Neuropsychopharmacology Exam 1
Questions And Answers
Receptor-binding process - ANS alters the cell's function
NT/hormone
Binds w/ receptor
Send signal to alter biological functions
Signal transduction
Transduce (convert) signal from outside to the inside of cell
ACh(neurotransmitter) - ANS Subtype: naCH receptor
Localization: hippocampus, cortex
Functions: cognitive, memory
Disorders: Alzheimer's
Drugs: Nicotine, Anticholinesterase
GABA - ANS Subtype: GABA(a)
Localization: Amygdala
Functions: Inhibits fear
Disorders: Anxiety disorder
Drugs: GABA, Barbiturate, Benzodiazepine, Progesterone, Alcohol
DA(dopamine) - ANS Subtype: D1
Localization: Basal ganglia, mesolimbic system, prefrontal cortex
Functions: BG: Motor initiation/termination
Mesolimbic system: Behavioral reinforcement by reward/pleasure center
PFC: Executive functions (CEO of the brain) (decision, judgements, working memory, etc.
, Disorders: Parkinson's disorder (degeneration of DA neurons in BG
Addiction (mesolimbic system) (insensitivity of D2)
ADHD (insensitivity of D4) (PFC)
Schizophrenia (PFC, excessive stim by DA)
Drugs: Cocaine, Amphetamine, Alcohol
Glu - ANS Subtype: Non-NMDA receptor
Localization: CNS
Functions: Generic excitatory NT receptor
One of the most common NT receptors
Disorders: Secondary injury in head trauma
Drugs: Excitotoxicity:
Kills post-synaptic neuron, blocker to prevent another injury
NE (norepinephrine)
(Noradrenaline)
EPI (epinephrine)
(Adrenaline) - ANS Subtypes: Alpha receptor, Beta receptor
Localization: Brainstem
Functions: Stimulates sympathetic response(fight or flight), wakes up cortex, increase HR and
BP
Disorders: Narcolepsy, coma
Drugs: AR- Ampethamine
BR- Beta blockers
Opioid receptor - ANS Subtype: Mu (m) subtype
Localization: Medthalamus- deep pain, analgesic effect
Brainstem- respiratory suppression
Functions: MT: Poor-localized, don't know where it is coming from, Require cortex to localize
Brainstem: CNS depressant
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