PHAR 100 EXAM QUESTIONS AND CORRECT ANSWERS (VERIFIED ANSWERS)|AGRADE
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PHAR 100
Institution
PHAR 100
PHAR 100 EXAM QUESTIONS AND CORRECT ANSWERS (VERIFIED ANSWERS)|AGRADE
Phase One Drug Trial - Answers - Small number of people
Absorption, distribution, elimination, and adverse effects are monitored
Phase Two Drug Trial - Answers - Small number of people
Determines if drug is effective in t...
PHAR 100 EXAM QUESTIONS AND
CORRECT ANSWERS (VERIFIED
ANSWERS)|AGRADE
Phase One Drug Trial - Answers -✔✔ Small number of people
Absorption, distribution, elimination, and adverse effects are monitored
Phase Two Drug Trial - Answers -✔✔ Small number of people
Determines if drug is effective in treatment
Phase Three Drug Trial - Answers -✔✔ Large number of people
Safety of drug is carefully studied
Potency - Answers -✔✔ Amount of drug that must be given to obtain a response
Efficacy - Answers -✔✔ Maximum effect of the drug
Paul Ehrlich - Answers -✔✔ Organoarsenic compounds
Salvarsan: syphilis treatment
Gerhard Domagk - Answers -✔✔ Sulfonamides
Prontosil: streptococcus
Antimetabolites - Answers -✔✔ Act against substances required for metabolism of an
organism
Example: sulfanilamide
Sulfanilamide - Answers -✔✔ Antimetabolite
Therapeutic Index - Answers -✔✔ Lethal Dose (Toxicity) ÷ Effective Dose
Higher means safer
Flumazenil - Answers -✔✔ Blocks effects of benzodiazepines
GABA antagonist
Zolpidem - Answers -✔✔ GABA receptor agonist
Does not disturb REM
Buspirone - Answers -✔✔ Acts on 5-HT receptor
Chloral Hydrate - Answers -✔✔ Old hypnotic
Diazepine - Answers -✔✔ Benzodiazepine Example
Flurazepam - Answers -✔✔ Benzodiazepine
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