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Walden 6630 Psychopharmacology Midterm Study Guide questions fully solved & updated 2025
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Walden 6630 Psychopharmacology Midterm Study Guide questions fully solved & updated 2025
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Walden 6630Psychopharmacology Midterm
Study Guide questions fully
solved & updated 2025
Serotonin regulates - answer Mood, emotion, feeding, and reproductive
behavior
This class of antidepressants binds to presynaptic SERT and inhibits them
from reuptake of serotonin to increase levels in the synaptic cleft to bind
with postsysnaptic 5HT2 receptors - answer SSRIs
First line therapy for MDD due to milder side effect profiles - answer SSRIs
Six Common SSRIs - answer citalopram, escitalopram, fluoxetine,
fluvoxamine, sertraline, paroxetine
Onset of therapeutic benefit from SSRIs - answer 4-6 weeks
In addition to MDD, SSRIs also treat - answer Chronic Anxiety, PTSD, OCD,
and eating disorders (bulimia)
Five Common side effects of SSRIs include - answer Anxiety, insomnia, GI
distress, sexual dysfunction (ED), SIADH
Severe side effect of SSRIs in children/adolescents under age 25 years old
- answer suicidal ideation
Life threatening adverse effect of SSRIs, especially when used in
combination with other serotonergic drugs (SNRIs, TCAs, MAOIs, etc.) -
answer Serotonin Syndrome
,Excess accumulation of serotonin resulting in overstimulation of the
nervous system - answer Serotonin Syndrome
Seven symptoms of Serotonin Syndrome - answer Flushing, hyperthermia,
agitation, muscle rigidity, seizure, coma, HYPERreflexia
The treatment for serotonin syndrome - answer Cyproheptadine (5-HT2
receptor antagonist)
Cyproheptadine treats serotonin syndrome by - answer blocking 5-HT2
receptors (serotonin antagonist)
When SSRIs or SNRIs are stopped abruptly, common symptoms of
withdrawal include - answer Irritability, headaches, and insomnia
Medicine specific side effect of citalopram - answer Prolonged QT interval
(normal=0.4.-0.44 seconds)
This SSRI is pregnancy category D due to associations with congenital
heart defects - answer Paroxetine
All SSRIs but paroxetine (D) are pregnancy category - answer C
Three SSRIs that are inhibitors of Cytochrome P450 enzymes - answer
fluoxetine, fluvoxamine, and paroxetine
Five common SNRIs include - answer duloxetine, venlafaxine,
desvenlafaxine, milnacipran, levomilnacipran
This antidepressant class of medications works by binding to presynaptic
SERT and NET to inhibit them from reuptake of serotonin and
norepinephrine to increase their levels in the synaptic cleft - answer SNRIs
, In addition to MDD SNRIs treat - answer Anxiety and neuropathic pain
(peripheral neuropathy)
Medication specific indications of duloxetine: - answer urinary
incontinence and Fibromyalgia
Medication specific indications of venlafaxine: - answer social anxiety,
panic disorders, PTSD, OCD, postmenopausal hot flashes
Six common side effects of SNRIs include: - answer Insomnia, nausea,
sexual dysfunction, hypertension, sweating, headaches
Severe side effect of SNRIs in children/adolescents under age 25 years old:
- answer suicidal ideation
Life threatening adverse effect of SNRIs, especially when used in
combination with other serotonergic drugs: - answer Serotonin Syndrome
This SNRI is an inhibitor of Cytochrome P450 enzymes: - answer
venlafaxine
This SNRI is hepatotoxic: - answer duloxetine
MAOIs increase the levels of: - answer Serotonin, Norepinephrine, and
Dopamine
Norepinephrine regulates: - answer alertness and focus
Dopamine regulates: - answer cognitive function, motivation, and
awakeness
In the synaptic cleft, Monoamine Oxidase A breaks down: - answer
Serotonin, Norepinephrine, and Dopamine
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