Exam (elaborations)
MCB FINAL EXAM LON CAPA + DISCUSSION QUESTIONS AND ANSWERS
- Course
- Institution
MCB FINAL EXAM LON CAPA + DISCUSSION QUESTIONS AND ANSWERS
[Show more]
Content preview
MCB FINAL EXAM LON CAPA + DISCUSSIONQUESTIONS AND ANSWERS
The figure above is a cartoon of the plus end of an individual
microtubule. Based on our discussion in lecture, which of the following
statements is correct? - Precise Answer ✔✔The plus end is shrinking
True or False: The two ends of a microtubule that is growing in vitro
(with neither end capped) have different critical concentrations. - Precise
Answer ✔✔True
Which of the following is/are MAPs?
Protein(s) that bind the GTP cap and promote assembly of microtubules
Proteins that promote bending of proto-filaments and promote
disassembly of microtubules
Proteins that bind the sides of microtubules and connect to other proteins
such as intermediate filament
Protein(s) that bind the GTP cap and promote assembly of microtubules,
and proteins that bind the sides of microtubules and connect to other
proteins such as intermediate filaments
All of the above - Precise Answer ✔✔All of the above
True or False: As described in lecture, microtubule assembly is best
described as an equilibrium reaction rather than a steady state reaction. -
Precise Answer ✔✔False
, True or False: As discussed in lecture, there are no known motor
proteins that move along intermediate filaments. - Precise Answer
✔✔True
By measuring microtubule growth, you find that they grow at a rate of 3
μm/min (this number has been altered to make the following calculation
easier). At this growth rate, approximately how many alpha/beta tubulin
dimers (8 nm in length) are added to the ends of a microtubule each
second (don't forget there are 13 protofilaments/microtubule)? - Precise
Answer ✔✔3000 nm/60 sec = 50 nm/sec x dimer/8 nm = ~6 dimers/sec
to each of 13 protofilaments = 78 tubulin dimers added per second
Dynamic instability causes microtubules to grow and shrink rapidly.
Consider a microtubule that is in its shrinking phase. Why is it
shrinking, and what must happen at the end of the microtubule for it to
stop shrinking and start growing? - Precise Answer ✔✔A microtubule
that is shrinking has more GDP than GTP. To begin growing a "GTP"
cap must be added so that it grows again.
True or False: As discussed in lecture, microtubules that are anchored in
a centrosome are nucleated by and are extensions of the microtubules
that comprise the centrioles. - Precise Answer ✔✔False
True or False: As discussed in lecture, within a centrosome the two
centrioles are identical to each other. - Precise Answer ✔✔False, one is
a mother and one is a daughter
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller YANCHY. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $16.49. You're not tied to anything after your purchase.
Can Stuvia be trusted?
4.6 stars on Google & Trustpilot (+1000 reviews)
75632 documents were sold in the last 30 days
Founded in 2010, the go-to place to buy study notes for 14 years now