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MSN571 Sect3 Advanced Pharmacology Week 1-4: Questions With Complete Solutions
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MSN571 Sect3 Advanced Pharmacology Week 1-4: Questions With Complete Solutions
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MSN571 Sect3 Advanced Pharmacology Week 1-4:Questions With Complete Solutions
Idiosyncratic effect Right Ans - an uncommon drug response resulting from
a genetic predisposition
Paradoxical effect Right Ans - the opposite of the intended drug response
Iatrogenic disease Right Ans - a condition that is caused by a medical
treatment
REMS Right Ans - Risk Evaluation and Mitigation Strategies
ADRB1 Right Ans - Causes beta1-Adrenergic receptors to be hypersensitive
VKORC1 Right Ans - Specific test available to determine the appropriate
dose for Warfarin to be therapeutic
HER2 Right Ans - growth factor gene highly activated in cells of certain
types of breast cancer
EGFR mutation Right Ans - epidermal human growth factor receptor,
tyrosine kinase activity, forms a dimmer with itself on cell membrane and
initiates cell signaling/proliferation
CCR5 coreceptor antagonist Right Ans - a drug that blocks the receptor site
on the T cell membrane that the HIV virus needs to interact with in order to
enter the cell
CCR5 Right Ans - along with the CD4+ receptor, this cell surface molecule is
used by HIV to fuse with the host's cell membranes
HLAs Right Ans - human leukocyte antigen... bodys defending cells aware of
an invader
Drug A Pregnancy Risk Factors Right Ans - Safest
, What is the pregnancy risk factor for drug B? Right Ans - More dangerous
than drug A
What is the pregnancy risk factor for drug C? Right Ans - More dangerous
than drugs A and B
What is the pregnancy risk factor for drug D? Right Ans - More dangerous
than drugs A, B, and C
What is the pregnancy risk factor for drug X Right Ans - Most dangerous;
known to cause fetal harm
Drugs causing growth suppression in peds Right Ans - glucocorticoids
Discoloration of developing teeth Right Ans - Tetracyclines
Kernicterus is caused by the effects of: Right Ans - occurs because of high
levels of unconjugated bilirubin. High levels of this pigment cross into the
central nervous system, causing brain damage to the infant.
Kernicterus causing drugs Right Ans - sulfonamides
Pediatric dosing guess based on body surface area Right Ans - Child's BSA X
Adult dosage /1.73
Beers list Right Ans - a list of drugs for which monitoring is especially
important in elderly patients
Pharmacokinetics Right Ans - what the body does to the drug
Pharmacodynamics Right Ans - what the drug does to the body
What type of drugs can cross the blood-brain barrier? Right Ans - Lipid-
soluble drugs
How does the blood-brain barrier prevent the entry of water-soluble drugs?
Right Ans - The blood-brain barrier has tight intercellular junctions that
prevent the entry of strongly ionized water-soluble drugs.
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