ABRAM’S CLINICAL DRUG THERAPY RATIONALES FOR
NURSING PRACTICE 13th EDITION GERALYN FRANDSEN’S
TESTBANK/COMPLETE GUIDE 2024-2025/ALL CHAPTERS 1-61
,Chapter 1: The Foundation of Pharmacology: Quality and Safety
1. A patient diagnosed with obsessive–compulsive disorder has been prescribed oral
paroxetine hydrochloride. What is the expected effect for this prescription?
A. Curative effect on symptoms
B. Systemic effect on symptoms
C. Local effect on symptoms
D. Parenteral effect on symptoms
ACCURATE ANSWER:-B
REASONING:->>>Pharmaceutical drug that produce systemic effects are taken into the
body, circulated through the bloodstream to their sites of action in various body tissues, and
eventually eliminated from the body. Curative agents are given to cure a disease process. In
this case, paroxetine hydrochloride will control the symptoms but not cure the disorder.
Pharmaceutical drug with local effects, such as sunscreen and local anesthetics, act mainly
at the site of application. Paroxetine hydrochloride is not administered parenterally.
Parenteral agentsare administered subcutaneously, intramuscularly, or intravenously.
POINTS: 1 REFERENCE: p. 3, Introduction OBJ: 1
NAT: Hospital client Needs: Physiological Integrity: Pharmacological and Parenteral
TherapiesTOP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety
KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Understand NOT: Multiple Choice
2. A hospital client has been prescribed an antibiotic. This pharmaceutical drug is a
naturally occurring substance that has been cheG
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name for this type of pharmaceutical drug?
A. Synthetic drug
B. Semisynthetic drug
C. Biotechnology drug
D. Prototype drug
ACCURATE ANSWER:-B
REASONING:->>>Semisynthetic pharmaceutical drug (e.g., many antibiotics) are
naturally occurring substances that have been chemically modified. Synthetic
pharmaceutical drug are more standardized in their chemical characteristics, more
consistent in their effects, and less likely to produce allergic reactions. Biotechnology
pharmaceutical drug involve manipulating DNAand RNA and recombining genes into
hybrid molecules that can be inserted into living organisms. Prototype pharmaceutical
drug are the first drug of a particular group to be developed.
POINTS: 1 REFERENCE: p. 3, Drug Sources OBJ: 1
NAT: Hospital client Needs: Physiological Integrity: Pharmacological and Parenteral
TherapiesTOP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety
KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Understand NOT: Multiple Choice
3. Which classification applies to morphine?
A. Central nervous system depressant
B. Central nervous system stimulant
, C. Anti-inflammatory
D. Antihypertensive
ACCURATE ANSWER:-A
REASONING:->>>Pharmaceutical drug are classified according to their effects on
particular body systems, their therapeutic uses, and their chemical characteristics. Morphine
is classified as a central nervous system depressant and will produce this effect in the
hospital client. Acentral nervous system stimulant increases attention and raises mood. An
anti-inflammatoryagent decreases inflammation at the site of tissue or joint inflammation.
An antihypertensiveagent reduces blood pressure.
POINTS: 1 REFERENCE: p. 3, Drug
Classifications and PrototypesOBJ: 1
NAT: Hospital client Needs: Physiological Integrity: Pharmacological and Parenteral
TherapiesTOP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety
KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Remember NOT: Multiple Choice
4. A hospital client is administered amoxicillin. The generic name of this pharmaceutical drug
belongs to whichdrug group?
A. Selective serotonin reuptake inhibitors
B. Diuretics
C. Penicillins
D. ACE inhibitors
ACCURATE ANSWER:-C
REASONING:->>>The generic name often indicates the drug group (e.g., pharmaceutical drug
GRADESBOOST.CO
with generic names ending in “cillin” are penicillins). Selective serotonin reuptake
inhibitors are pharmaceutical drugs
that have antidepressant effects; SSRI is a broad classification, not a generic name. Diuretics
are pharmaceutical drugs that increase urine output; diuretic is a broad classification, not a
generic name. ACE inhibitor is the broad classification for the angiotensin receptor blockers,
not thegeneric name.
POINTS: 1 REFERENCE: p. 3, Drug Names OBJ: 2
NAT: Hospital client Needs: Physiological Integrity: Pharmacological and Parenteral
TherapiesTOP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety
KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Understand NOT: Multiple Choice
5. The administration of diphenhydramine is regulated by which U.S. government agency?
A. Public Health Service
B. Federal Trade Commission
C. Occupational Safety and Health Administration
D. Food and Drug
Administration
ACCURATE ANSWER:-D
, REASONING:->>>The Food and Drug Administration approves pharmaceutical drug for
over- the-counter availability, including the transfer of pharmaceutical drug from
prescription to OTC status, and may require clinical trials to determine the safety and
effectiveness of OTC use.The Public Health Service is regulated by the state to maintain
the health of individual citizens of the state. The Federal Trade Commission regulates
imports and exports throughout the nation. The Occupational Safety and Health
Administration regulates safety within the workplace.
POINTS: 1 REFERENCE: p. 4, Prescription and Nonprescription
Pharmaceutical drug OBJ: 4
NAT: Hospital client Needs: Physiological Integrity: Pharmacological and Parenteral
TherapiesTOP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety
KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Understand NOT: Multiple Choice
6. In the U.S., the administration of anabolic steroids is regulated by which law?
A. The Food, Drug, and Cosmetic Act of 1938
B. The Comprehensive Drug Abuse Prevention and Control Act
C. The Harrison Narcotic Act
D. The Sherley Amendment
ACCURATE ANSWER:-B
REASONING:->>>The Comprehensive Drug Abuse Prevention and Control Act regulates
the manufacture and distribution of narcotics, stimulants, depressants, hallucinogens, and
anabolic steroids. The Food, Drug, and Cosmetic Act of 1938 revised and broadened FDA
powers and responsibilities, giving the FDA control over drug safety. The Harrison Narcotic
Act restricted the importation, manufacture, sale, and use of opium,cocaine, marijuana, and
other pharmaceutical drug that the act d e f i Gn eRd Aa Ds E
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erley Amendment of
1912 prohibited fraudulent claims of drug effectiveness.
POINTS: 1 REFERENCE: p. 4, Prescription and Nonprescription
Pharmaceutical drug OBJ: 3
NAT: Hospital client Needs: Physiological Integrity: Pharmacological and Parenteral
TherapiesTOP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety
KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Remember NOT: Multiple Choice
7. A nursing attendant is responsible for maintaining an accurate count and record of the
controlled substances on the nursing division. This nursing action is regulated by which
U.S. law or agency?
A. The Food, Drug, and Cosmetic Act of 1938
B. The Public Health Service
C. The Drug Enforcement Administration
D. The Sherley Amendment
ACCURATE ANSWER:-C
