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Pharmacology Psychiatric Mental Health Nurse Practitioner Exam Questions With 100% Verified Answers

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Pharmacology Psychiatric Mental Health Nurse Practitioner Exam Questions With 100% Verified Answers What are the five factors that influence absorption? - answerGastric emptying Time of contact with intestinal wall Bowel perfusion Food Formation of non-absorbable complexes Explain the hepat...

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  • November 12, 2024
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©THEBRIGHT EXAM SOLUTIONS

11/05/2024 12:06 PM


Pharmacology Psychiatric Mental Health
Nurse Practitioner Exam Questions With
100% Verified Answers



What are the five factors that influence absorption? - answer✔Gastric emptying

Time of contact with intestinal wall

Bowel perfusion

Food

Formation of non-absorbable complexes

Explain the hepatic first pass. - answer✔Part of the drug is metabolized by the liver before it reaches the
blood.

Explain bioavailability. - answer✔Percentage of administered drug that reaches systemic circulation.

Name the 3 highly water-soluble drugs. - answer✔Lithium, Amisulpride, Paliperidone

What are the 7 inhibitors of CYP? - answer✔Paroxetine, Fluoxetine, Fluvoxamine, Fluconazole,
Ciprofloxacin, Ritonavir, Grapefruit juice

What are the 6 inducers of CYP? - answer✔Carbamazepine, Phenytoin, Phenobarbital, Primidone,
smoking, St-John's Wort

What are the 6 factors that influence pharmacokinetics? - answer✔Age, pregnancy, obesity, sexe,
comorbidities, genetics

Explain the half-life. - answer✔The time it takes for the concentration of a drug to be reduced by 50%

What are the 11 indications for TDM. - answer✔Non-compliance/toxicity

Lack of efficacy/adverse effects at normal dose

Relapse in maintenance treatment

, ©THEBRIGHT EXAM SOLUTIONS

11/05/2024 12:06 PM

Change in drug formulation

Pregnancy

Age

Comorbidities

Drug interactions

Change in BMI

Finding the optimal drug concentration

Genetic polymorphisms

What are the 4 factors influencing receptor binding? - answer✔Affinity

Specificity

Saturability

Reversibility

Define intrinsic activity. - answer✔The ability of a drug to initiate a response after binding to a receptor

Define complete agonist vs. partial agonist. - answer✔Decreased intrinsic activity, decreased
pharmacological effect, good affinity with receptor

Define competitive antagonist vs. non-competitive antagonist. - answer✔Differences in dose response
curves

Increasing dose of agonist will change the response of a competitive antagonist.

What are the 4 targets of psychotropic drugs? - answer✔Transporters, G-coupled protein receptor, ion
channels, enzymes

What is tachyphylaxis? - answer✔Neurotransmitter depletion

What drugs are involved in induced psychotic disorders? - answer✔Dopamine agonists Chloroquine

Corticosteroids

Fluoroquinolones

Stimulants

What are the side effects of Cogentin? - answer✔Dry mouth

Mydriasis

Blurred vision

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