©THEBRIGHT EXAM SOLUTIONS
11/8/2024 12:08 PM
NURS 5463 Quiz 2 Study Guide
Bladder Cancer Metastasis - answer✔Bone, liver, lung
Breast Cancer Metastasis - answer✔Bone, brain, liver, lung
Colorectal Cancer Metastasis - answer✔Liver, lung, peritoneum
Kidney Cancer Metastasis - answer✔Adrenal gland, bone, brain, liver, lung
Lung Cancer Metastasis - answer✔Adrenal gland, brain, liver, bone
Melanoma Metastasis - answer✔Bone, brain, liver, lung, skin, muscle
Ovarian Cancer Metastasis - answer✔Liver, lung, peritoneum
Pancreatic Cancer Metastasis - answer✔Liver, lung, peritoneum
Prostate Cancer Metastasis - answer✔Adrenal gland, bone (commonly to vertebrae), liver, lung
Stomach Cancer Metastasis - answer✔Liver, lung, peritoneum
Testicular Cancer Metastasis - answer✔Lungs, liver, brain
Thyroid Cancer Metastasis - answer✔Bone, liver, lung
Uterine Cancer Metastasis - answer✔Bone, liver, lung, peritoneum, vagina
Alpha-fetoprotein - answer✔Tumor marker for hepatocellular carcinoma and testicular cancer
Carcinoembryonic Antigen (CEA) - answer✔Tumor marker for colorectal cancer
Beta Human Chorionic Gonadotropin (b-HCG) - answer✔Tumor marker for choriocarcinomas,
teratomas, and seminomas
Prostate Specific Antigen (PSA) - answer✔Tumor marker for prostate cancer
CA-125 - answer✔Tumor marker for ovarian cancer
CA19-9 - answer✔Tumor marker for pancreatic cancer, gall bladder cancer, and bile duct cancer
CA15-3 - answer✔Tumor marker for breast cancer
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11/8/2024 12:08 PM
CA27-29 - answer✔Tumor marker for breast cancer
Cyclophosphamide (Cytoxan) Adverse Effects - answer✔Alopecia, myelosuppression, hemorrhagic
cystitis, cardiotoxicity in high doses
Ifosfamide (Ifex) Adverse Effects - answer✔Alopecia, myelosuppression, hemorrhagic cystitis,
neurotoxicity
Carboplatin (Paraplatin) Adverse Effects - answer✔Myelosuppression, electrolyte imbalance, peripheral
neuropathy, nephrotoxicity
Cisplatin (Platinol) Adverse Effects - answer✔Myelosuppression, electrolyte imbalance, peripheral
neuropathy, nephrotoxicity
Methotrexate (MTX) Adverse Effects - answer✔Myelosuppression, nephrotoxicity, hepatotoxicity,
neurotoxicity, photosensitivity, pulmonary toxicity
Dacarbazine (DTIC) Adverse Effects - answer✔Photosensitivity, myelosuppression, anorexia,
hypotension, flu-like symptoms
Cytarabine (Ara-C) Adverse Effects - answer✔Nausea/vomiting, rash, flu-like symptoms,
myelosuppression, neurotoxicity, ocular toxicity
Fluorouracil (5-FU) Adverse Effects - answer✔Diarrhea, myelosuppression, mucositis, photosensitivity,
cardiotoxicity
Gemcitabine (Gemzar) Adverse Effects - answer✔Nausea/vomiting, rash, flu-like symptoms, fever,
diarrhea, myelosuppression, edema, elevated transaminases
Vinblastine (Velban) Adverse Effects - answer✔Constipation, myelosuppression, alopecia, bone pain,
malaise, toxic effects on the colon
Vincristine (Oncovin) Adverse Effects - answer✔Constipation, toxic effects on the colon, peripheral
neuropathy, alopecia
Paclitaxel (Taxol) Adverse Effects - answer✔Diarrhea, myelosuppression, peripheral neuropathy,
alopecia, edema, mucositis
Danuorubicin (Cerubidine) Adverse Effects - answer✔Nausea/vomiting, diarrhea, red/orange urine,
myelosuppression, dose related cardiotoxicity
Doxorubicin (Adriamycin) Adverse Effects - answer✔Nausea/vomiting, diarrhea, red/orange urine,
myelosuppression, dose related cardiotoxicity
Etoposide (Vepesid) Adverse Effects - answer✔Nausea/vomiting, diarrhea, fever, hypotension,
myelosuppression, alopecia, fatigue
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11/8/2024 12:08 PM
Prolonged aPTT, Normal PT/INR - answer✔- von Willebrand Diesase
- Factor deficiencies: VIII, IX, XI, XII, prekallikrein, HMW kininogen
- Heparin
- Lupus anticoagulant
Normal aPTT, Prolonged PT/INR - answer✔- Liver disease
- Vitamin K deficiency
- Warfarin
Prolonged aPTT, Prolonged PT/INR - answer✔- Issue in the Common Pathway
- Deficiency of prothrombin, fibrinogen, factor V, or factor X
- Combined factor deficiencies
- Diseases such as liver disease, DIC, over coagulation with warfarin
- Draw a thrombin time. If normal the issue lies with abnormalities in factors II, V, or X
Normal aPTT, Normal PT/INR, but Bleeding - answer✔- von Willebrand Disease
- Platelet dysfunction
- Thrombocytopenia
Proximal DVT - answer✔Above the knee
- Popliteal, femoral, iliac
- Superficial femoral vein is considered deep vein
- 80% of symptomatic DVTs
**Higher mortality and complication rate than distal DVTs**
Distal DVT - answer✔Below the knee
- Typically confined to calf veins
- 80% will resolve without anticoagulation
DVT Risk Factors - answer✔Previous VTE, inheritable coagulopathy, hospitalization within the last 3
months, COPD & CHF exacerbations,
