Any treatment for for a SUD that includes a pharmacologic intervention as part of a comprehensive
substance abuse treatment plan with ultimate goal of patient recovery with full social function -
answer✔Medication Assisted Treatment (MAT)
FDA approved disulfiram, naltrexone, and acamprosate for treatment of ____________ -
answer✔alcohol dependence
FDA approved methadone, naltrexone, and buprenorphine for treatment of _____________ -
answer✔opioid dependence
currently, FDA has approved medications effective for MAT in three types of SUD: _____________,
_____________ and __________ dependence - answer✔alcohol, nicotine and opioid
three drugs approved for alcohol dependence - answer✔acamprosate, disulfiram, naltrexone
used to treat alcohol dependence; reduces symptoms of protracted withdrawal (i.e. insomnia, anxiety,
restlessness, and dysphoria) by normalizing brain systems disrupted by chronic alcohol consumption;
more effective in pts with severe alcohol use disorders - answer✔Acamprosate (Campral)
used to treat alcohol dependence; inhibits an enzyme involved in the metabolism in alcohol, causing
unpleasant reaction (i.e. flushing, nausea, and heart palpitations) if alcohol is consumed after taking the
medication; compliance can be a problem but is very effective with motivated pts. - answer✔Disulfiram
(Antabuse)
used to treat alcohol dependence; blocks receptors involved in rewarding effects of drinking and in
cravings for alcohol. Reduces relapse of heavy drinking behavior and is highly effective in some but not
all pts., where varied outcomes could be due to genetic factors. Available in both oral tablet and long-
acting injectable form - answer✔Naltrexone (Vivitrol or Revia)
three FDA approved drugs used in MAT for opioid use disorders - answer✔Methadone, Buprenorphine,
Naltrexone
prevents opioid withdrawal and craving symptoms by activating opiate receptors in the brain. Long
history of use in treatment of opioid dependence. - answer✔Methadone
reduces or eliminates opioid withdrawal symptoms and reduces cravings, without producing euphoria or
dangerous side effects of heroin or other opioids. Activates and blocks opioid receptors in the brain.
Available for sublingual administration in both a stand-alone formula and in combination with naloxone.
- answer✔Buprenorphine
approved for prevention of relapse in adult pts. following complete detox from opioids. Acts by blocking
brain's opioid receptors, preventing opioid drugs from acting on them and thus blocking euphoria the
user would normally feel and/or causing withdrawal if recent opioid use has occurred. Can be taken
orally or given in monthly injections - answer✔Naltrexone (Vivitrol or Revia)
medication used to prevent opioid overdose deaths. Medication binds to opioid receptors and can
rapidly reverse or block the effects of other opioids. - answer✔Naloxone (Narcan)
form of behavioral therapy that can help people learn new skills to maintain a substance-free life,
address co-occurring mental health issues, address benefits of using prescription medication in
treatment, and support individuals to pursue meaningful work, school, and family goals -
answer✔Individual therapy
form of behavioral therapy that can help reduce a person's sense of isolation, provide peer support and
feedback, and develop social and problem-solving skills - answer✔Group counseling
form of behavioral therapy that provides education, allows family members to express their feelings and
concerns, and helps secure the family's support for the person in recovery - answer✔Family behavior
therapy
form of behavioral therapy; seeks to help patients recognize, avoid, and cope with situations in which
they are most likely to abuse drugs - answer✔Cognitive-behavioral therapy
form of behavioral therapy; capitalizes on readiness of individuals to change their behavior and enter
treatment - answer✔Motivational enhancement
form of behavioral therapy; uses positive reinforcement to encourage abstinence from drugs -
answer✔Motivational incentives
first medication approved by FDA to treat chronic alcohol dependence; alcohol-aversive or alcohol-
sensitizing agent; does not affect brain receptors directly - answer✔Disulfiram (Antabuse)
Disulfiram (Antabuse) is most effective for pts. who have undergone detoxification or are in initiation
stage of abstinence, especially when committed to abstinence and receive adequate, ongoing
supervision - answer✔true
relatively long-lasting opioid antagonist; used to treat opioid dependence for many years and used to
treat alcohol dependence sine 1994; reduces both the rewarding effects of alcohol and craving for it -
answer✔Oral naltrexone (Revia)
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