LATG - Laboratory Animal Technologist: Questions
With Solutions
What is one of the main factors that determine the number of sentinels used?
Space available in the animal room Right Ans - Expected morbidity of the
agents being monitored
How often must the PHS assurance be resubmitted? Right Ans - Every 5
years
The USDA APHIS Annual Report of Enforcement is based in part on which of
the following? Right Ans - Annual reports submitted to USDA by registered
facilities
Which statement best applies to Good Laboratory Practices regulations?
Right Ans - They apply to nonclinical studies for the assessment of the safety
of chemicals to humans, animals, and the environment.
The AWA Regulations and PHS Policy both require that the IACUC conduct
semiannual inspection of all areas where live animals are housed or used.(t/f)
Right Ans - True
Which of the following is often referred to as the Worker Right-to-Know
legislation? Right Ans - OSHA's Hazard Communication Standard
Health and Consumer Protection Directorate General
Which agency is authorized to develop regulations based on the Animal
Welfare Act? Right Ans - USDA
The NRC regulates use of nuclear materials for medical and academic uses
through regulations, licensing, and safety oversight.(t/f) Right Ans - True
All medical waste should be considered infectious.(t/f) Right Ans - false
How often should a research facility using regulated species update their
USDA registration? Right Ans - Every 3 years
Which statement best describes AAALAC's program status evaluation?
,It is conducted every 2 years. Right Ans - It is a confidential peer review
process.
OLAW requires that institutions submit an assurance document affirming that
they will comply with all PHS policy requirements.(t/f) Right Ans - True
Which agency administers the Animal Welfare Act? Right Ans - APHIS
Which institutional office generally has the responsibility for monitoring the
handling of radioactive materials in the laboratory? Right Ans - Radiation
Safety Office
Which of the following are mandated by the Animal Welfare Act? Right Ans
- Information on how to report deficiencies in animal care
Establishment of an IACUC
Training of all animal care personnel
Which of the following steps are recommended in managing inspections?
Right Ans - Develop an SOP outlining the process to follow for an inspection.
What additional publication from USDA clarifies the intent of the Animal
Welfare Act? Right Ans - The Animal Care Policy Manual
GLP Regulations describe the training requirements for personnel involved in
covered studies.(t/f) Right Ans - true
Under no circumstances can a manufacturer withhold information about a
potentially hazardous material.(t/f) Right Ans - false
Which organization has developed standards and guidelines to help prevent
the transmission of zoonoses through importation of animals? Right Ans -
The World Organization for Animal Health
Which statement correctly describes the PHS assurance? Right Ans - It
must describe the essential components of an institution's animal care and
use program
Which agency has regulations or guidelines that regulate the transportation of
animals? Right Ans - US Fish and Wildlife Service
,FDA
US Department of Transportation
Which assurance must be included by research institutions in the annual
report to USDA? Right Ans - Professionally acceptable standards of care,
treatment, and use were followed and documented.
To be compliant with OLAW, which document should be the basis of the
IACUC review of the institution's program for the use and care of animals?
Right Ans - The Guide for the Care and Use of Laboratory Animals
Which statement applies to semiannual inspections conducted by the IACUC?
Right Ans - The IACUC can use the Guide as the basis for the inspection.
The CDC is one of the agencies that regulates the care and welfare of research
animals(t/f) Right Ans - false
Which group of compounds falls within the scope of GLP Regulations?
Right Ans - Veterinary drugs
Food and color additives
Biological products
Which regulatory agencies codifies GLP Regulations for laboratory studies?
Right Ans - EPA
FDA
OECD
Research facilities using regulated species must register with USDA and the
registration must be updated every year.(t/f) Right Ans - False
All regulations regarding obtaining, storing, and disposing of controlled
substances are federal statutes.(t/f) Right Ans - False
Serology is the best method to detect pathogens in immunodeficient animals.
(t/f) Right Ans - False
Serological tests conducted on samples taken when animals arrive at the
facility provide information about their health status at which period of time?
Right Ans - 2 weeks before shipment
, What does the acronym "CFUs" stand for? Right Ans - Colony forming units
Which of the animals described below would be best to use as a sentinel in a
room housing a mouse colony? Right Ans - 4-month old mouse
What can the multiplex fluorescent immunoassay detect? Right Ans -
Presence of viral antibodies
A postmortem cecal exam is used to detect: Right Ans - Aspiculuris
Radios should not be permitted in any room where animals are housed.(t/f)
Right Ans - True
Which kind of feed does a facility that must meet GLP standards most likely
use? Right Ans - Certified diets
Continuous exposure to acoustical levels above what level can have both
auditory and non-auditory effects? Right Ans - 85 db
Sentinel animals should be at least what age? Right Ans - 8-12 weeks
What is the term for natural mutations that occur in isolated colonies?
Right Ans - Genetic drift
The highest risk for introducing pathogens into an animal facility is through
which of the following? Right Ans - Introduction of live animals
What is the term for the systematic approach to ensuring that a program
meets specified requirements? Right Ans - Quality assurance
Regulations and standards for USDA- regulated species are specified in which
of the following? Right Ans - Animal Welfare Act
What is a common method used to detect exposure to viral pathogens?
Right Ans - ELISA
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