100% satisfaction guarantee Immediately available after payment Both online and in PDF No strings attached
logo-home
Pediatric Acute Lymphoblastic Leukemia Exam Questions with Verified Answers (Graded A+) $7.99   Add to cart

Exam (elaborations)

Pediatric Acute Lymphoblastic Leukemia Exam Questions with Verified Answers (Graded A+)

 0 view  0 purchase
  • Course
  • Pediatric Acute Lymphoblastic Leukemia
  • Institution
  • Pediatric Acute Lymphoblastic Leukemia

Pediatric Acute Lymphoblastic Leukemia Exam Questions with Verified Answers (Graded A+) What is risk stratum of pediatric ALL using patient case? - Answers What labs are suggestive of ALL? - Answers WBC: 70.3 (5-15 is normal) Hgb: 5.8 (10.5-13.5) Plt: 36 (150 - 400) Blasts: 89.0 Wha...

[Show more]

Preview 2 out of 8  pages

  • November 11, 2024
  • 8
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers
  • Pediatric Acute Lymphoblastic Leukemia
  • Pediatric Acute Lymphoblastic Leukemia
avatar-seller
TutorJosh
Pediatric Acute Lymphoblastic Leukemia Exam Questions with Verified Answers (Graded A+)

What is risk stratum of pediatric ALL using patient case? - Answers

What labs are suggestive of ALL? - Answers WBC: 70.3 (5-15 is normal)



Hgb: 5.8 (10.5-13.5)



Plt: 36 (150 - 400)



Blasts: 89.0

What is the etiology? - Answers most common pediatric malignancy (leading cause of childhood cancer
death)



overall survival rates currently ~90%



peak incidence 2-5 years old



boys > girls, white hispanic > Black, Asian



higher incidence in industrial countries

Diagnosis of ALL? - Answers symptoms are are non-specific



procedures (bone marrow biopsy and lumbar puncture)

Pathophysiology of ALL? - Answers T lymphocyte (10%)



B lymphocyte (90%)

What is CNS Status? - Answers CNS 1: no leukemia cells present on CSF studies

, CNS 2: less than 5 WBCs + Blasts on CSF studies



CNS 3: greater than equal to 5 WBCs + Blasts on CSF studies

What is important to know about intrathecal chemo? - Answers direct injection into CNS



used for both treatment of CNS disease and prophylaxis against development of CNS disease (systemic
chemo has limited CNS penetration)



limited systemic penetration



*most common - intrathecal cytarabine*

- may also give methotrexate or "triple IT" (cytarabine + methotrexate + hydrocortisone)

What is the treatment of TLS? - Answers start hydration at 1.5 to 2x maintenance rate



give *single dose of raburicase 0.2mg/kg; cap dose at 6mg* --expensive / will not get rid of new uric acid
production



*start allopurinol 10/mg/kg/day divided TID* --inhibit xanthine oxidase and prevent uric acid crystals



*start sevelamer 800mg TID with meals* -- prevent calcium / phosphorus precipitate formation -- does
not do anything for the phos that is there (this is a phos binder)

What is TLS? - Answers tumor lysis syndrome (fairly common in ALL)



tumor cells lyse (either spontaneously or as a result of chemotherapy) -- will release all of the
intracellular components (DNA)

The benefits of buying summaries with Stuvia:

Guaranteed quality through customer reviews

Guaranteed quality through customer reviews

Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.

Quick and easy check-out

Quick and easy check-out

You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.

Focus on what matters

Focus on what matters

Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!

Frequently asked questions

What do I get when I buy this document?

You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.

Satisfaction guarantee: how does it work?

Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.

Who am I buying these notes from?

Stuvia is a marketplace, so you are not buying this document from us, but from seller TutorJosh. Stuvia facilitates payment to the seller.

Will I be stuck with a subscription?

No, you only buy these notes for $7.99. You're not tied to anything after your purchase.

Can Stuvia be trusted?

4.6 stars on Google & Trustpilot (+1000 reviews)

67096 documents were sold in the last 30 days

Founded in 2010, the go-to place to buy study notes for 14 years now

Start selling
$7.99
  • (0)
  Add to cart