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Childhood Acute Lymphoblastic Leukemia Exam Questions and Answers 100% Correct

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Childhood Acute Lymphoblastic Leukemia Exam Questions and Answers 100% Correct ALL anatomy - Answers Childhood ALL originates in the T- and B-lymphocytes in the bone marrow Marrow involvement of acute leukemia as seen by light microscopy is defined as follows: M1: Fewer than 5% blast cells. M...

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  • November 11, 2024
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  • 2024/2025
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  • Childhood Acute Lymphoblastic Leukemia
  • Childhood Acute Lymphoblastic Leukemia
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Childhood Acute Lymphoblastic Leukemia Exam Questions and Answers 100% Correct

ALL anatomy - Answers Childhood ALL originates in the T- and B-lymphocytes in the bone marrow
Marrow involvement of acute leukemia as seen by light microscopy is defined as follows:



M1: Fewer than 5% blast cells.

M2: 5% to 25% blast cells.

M3: Greater than 25% blast cells.

Most patients with acute leukemia present with an M3 marrow

ALL Incidence and Epidemiology - Answers ALL is the most common cancer diagnosed in children and
represents 23% of cancer diagnoses among children younger than 15 years.

ALL occurs at an annual rate of approximately 30 to 40 cases per million people in the United States.
There are approximately 2,900 children and adolescents younger than 20 years diagnosed with ALL each
year in the United States.

Over the past 25 years, there has been a gradual increase in the incidence of ALL.

Risk Factors for Developing ALL - Answers •Prenatal exposure to x-rays.



•Postnatal exposure to high doses of radiation (e.g., therapeutic radiation as previously used for
conditions such as tinea capitis and thymus enlargement).



•Genetic conditions that include the following:

Down syndrome.

Neurofibromatosis

Shwachman syndrome

Bloom syndrome.

Ataxia telangiectasia



•Inherited genetic polymorphisms.

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