What is the source of the extra chromosome 21 in an individual with Down syndrome?
a) nondisjunction in the mother only
b) nondisjunction in the father only
c) duplication of the chromosome
d) nondisjunction or translocation in either parent
e) it is impossible to detect with current technology Correct Ans-nondisjunction or
translocation in either parent
The following is a map of four genes on a chromosome: Figure 15.1. Between which two genes
would you expect the highest frequency of recombination? Correct Ans-A and G
In his transformation experiments, what did Griffith observe?
a) Mutant mice were resistant to bacterial infections.
b) Mixing a heat-killed pathogenic strain of bacteria with a living nonpathogenic strain can
convert some of the living cells into the pathogenic form.
, c) Mixing a heat-killed nonpathogenic strain of bacteria with a living pathogenic strain makes
the pathogenic strain nonpathogenic.
d) Infecting mice with nonpathogenic strains of bacteria makes them resistant to pathogenic
strains.
e) Mice infected with a pathogenic strain of bacteria can spread the infection to other
mice. Correct Ans-b) Mixing a heat-killed pathogenic strain of bacteria with a living
nonpathogenic strain can convert some of the living cells into the pathogenic form.
At a specific area of a chromosome, the sequence of nucleotides below is resent where the
chain opens to form a replication fork: 3' C C T A G G C T G C A A T C C 5'. An RNA primer is
formed starting at the underlined T (T) of the template. Which of the following represents the
primer sequence?
a) 5' G C C T A G G 3'
b) 3' G C C T A G G 5'
c) 5' A C G T Y A G G 3'
d) 5' A C G U U A G G 3'
c) 5' G C C U A G G 3' Correct Ans-d) 5' A C G U U A G G 3'
What is the effect of a nonsense mutation in a gene?
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