Exam (elaborations)
AG-ACNP Boards – endocrine Questions and Answers
- Course
- Institution
AG-ACNP Boards – endocrine Questions and Answers
[Show more]
Content preview
AG-ACNP Boards – endocrine Questionsand Answers
SIADH Correct Ans--Inappropriate Water RETENTION, release of ADH occurs independent
of osmolality or volume dependent stimulation
-2/2 paraneoplastic syndrome classically lung, CNS disorder, Chronic lung disease, pneumonia,
skull fx/head trauma
S/S of SIADH Correct Ans--Neurologic changes: mild H/A, seizures, coma (D/T
hyponatremia)
-Decreased DTRs
-hypothermia/cold intolerance
-weight gain/edema
-n/v
Lab/Diagnosis of SIADH Correct Ans-Hyponatremia: yet euvolemic
Decreased serum osmolality (<280)
,Increased urine osmolality (>100)
Urine Sodium >20
Renal, cardiac, thyroid function normal
SIADH urine sodium Correct Ans--Na+ handling is regulated by aldosterone - hypervolemia
= low aldosterone production = high Na excretion.
-the urine Na+ concentration reflects Na+ intake, which is generally more than 40 mEq/d
(usually 50-100 mEq/d)
SIADH treatment Correct Ans-*fluid restriction
*treatment of underlying disorder
*ADH receptor antagonist:
-Demeclocycline
-lithium
-vasopressin receptor antagonists
, SIADH fluid restriction guidelines Correct Ans-Mild (asymptomatic with sodium 120-130
meq/L) = 1000ml/24h Fl R
Moderate (asymptomatic with sodium 110-120 meq/L) = 500ml/24h Fl R
Severe (symptomatic) = Loop diuretic + normal saline 0.9% or hypertonic saline 3% saline
Diabetes Insipidus Correct Ans-*Central: Related to pituitary or hypothalamus damage
resulting in ADH deficiency
*Nephrogenic: due to defect in the renal tubules resulting in renal insensitivity to ADH.
-Acquired due to phelonephritis
-K+ depletion
-sickle cell anemia
-chronic hypercalcemia causing renal failure
-medications (lithium, demeclocycline)
S/S of DI Correct Ans--Fluid intake 5-20L/day
-polyuria 2-20L/day
-weight loss, fatigue, tachycardia, hypotension
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller ExamRoom. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $14.99. You're not tied to anything after your purchase.
Can Stuvia be trusted?
4.6 stars on Google & Trustpilot (+1000 reviews)
67866 documents were sold in the last 30 days
Founded in 2010, the go-to place to buy study notes for 14 years now