MEDT 405 FINAL EXAM | 150 QUESTIONS |
WITH COMPLETE SOLUTIONS!!
Which of the following describes the body mechanism that helps to regulate
iron toxicity so that less iron is absorbed?
A. hepatocytes release hepcidin which inactivates transferrin in the enterocyte
B. hepatocytes stop producing hepcidin leading to an increase in transferrin
saturation
C. hepatocytes release hepcidin which inactivates ferroportin in the enterocyte
D. hepatocytes stop producing hepcidin leaving ferroportin in the enterocyte to
facilitate iron transport Answer - hepatocytes release hepcidin which
inactivates ferroportin in the enterocyte
The test that is most useful in differentiating Fanconi's Anemia from other
causes of pancytopenia is:
A. bone marrow biopsy
B. flow cytometric analysis of CD55
C. Diepoxybutane-induced chromosome breakage
,D. Ham acidified serum test Answer - Diepoxybutane-induced chromosome
breakage
Macrophage-mediated hemolysis is:
A. intramedually hemolysis
B. myeloproliferative hemolysis
C. intravascular hemolysis
D. extravascular hemolysis Answer - extravascular hemolysis
All of the following is true regarding Stage 1 of iron deficiency, except:
A. serum ferritin levels are low
B. patients are devoid of symptoms of anemia
C. RBC development is normal
D. serum ferritin levels are normal Answer - serum ferritin levels are normal
Which of the following stains blue with Prussian blue stain?
A. apoferritin
B. transferrin
,C. hemosiderin
D. ferritin Answer - hemosiderin
How are malaria parasites identified in the hematology laboratory?
A. blood cultures
B. PCR
C. thick and thin peripheral blood smears
D. indirect fluorescent test Answer - thick and thin peripheral blood smears
Treatment of pernicious anemia, to bypass the need for intrinsic factor, is:
A. vitamin B12 given intramuscularly
B. folate given intramuscularly
C. increasing intake of green vegetables
D. increasing intake of red meat Answer - vitamin B12 given intramuscularly
Why is G6PD important for normal red cell survival?
A. it is required for insertion of iron into the protoporphyrin ring to form heme
B. it is required to regenerate reduced glutathione
, C. alpha chains are produced in excess in its absence
D. hemoglobin oxygen affinity is increased in its absence Answer - it is required
to regenerate reduced glutathione
Which of the following lab results are consistent with anemia of chronic
inflammation?
A. normal serum ferritin, increased TIBC, increased serum iron
B. decreased serum ferritin, decreased TIBC, increased serum iron
C. decreased TIBC, decreased serum ferritin, increased serum iron
Which of the following disorders describes red cells that acquire a reduced
surface area from losing unsupported membrane when defective proteins
disrupt vertical interactions between transmembrane proteins and the
cytoskeleton?
A. spherocytosis
B. acanthocytosis
C. pyropoikilocytosis
D. stomatocytosis Answer - spherocytosis
All of the following is true regarding Stage 3 iron deficiency, except:
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