MGCCC Nursing Pharmacology
Sulf Sulfamethoxazole-Trimethoprim/TMP-SMZ (Nursing Interventions) -
✔️✔️Administer with full glass of water 1 hour before meals or 2 hours after meals.
Increase fluid intake.
Monitor for sore throat, bruising, bleeding.
Monitor CBC.
Check for superinfection.
Advise client not to take with antacids.
Tell client to avoid direct sunlight.
Use alternate forms of OCP
Avoid OTC (asa, vit.C)
Nitrofurantoin (Macrodantin) (side effects) - ✔️✔️Dizziness, h/a, drowsiness, peripheral
neuropathy, chills, confusion, vertigo, CP, n/v/d, abd pain, loss of appetite, pruritus,
rash, angioedema, alopecia, tooth staining, arthralgia, myalgia, numbness, cough,
dyspnea, pneumonitis, pulmonary fibrosis or infiltrate, SLE-like syndrome
amethoxazole-Trimethoprim/TMP-SMZ (Actions) - ✔️✔️Inhibit bacterial synthesis of
folic acid
Bacteriostatic
Fights gram - bacteria
Proteus, Klebsiella, E. coli, Chlamydia
Sulfamethoxazole-Trimethoprim/TMP-SMZ (uses) - ✔️✔️Otitis media, respiratory
infections
UTIs, prostatitis, gonorrhea
Sulfamethoxazole-Trimethoprim/TMP-SMZ (Routes) - ✔️✔️Oral, IV, topical, ophthalmic
Sulfamethoxazole-Trimethoprim/TMP-SMZ (Contraindications) - ✔️✔️Br feeding
infants <2mo. Hypersensitivity, term pregnancy, megaloblastic anemia, chancroid,
traveler's diarrhea
Sulfamethoxazole-Trimethoprim/TMP-SMZ (Side Effects) - ✔️✔️Mild to moderate rash,
photosensitivity
GI distress, stomatitis, crystalluria
Fatigue, depression, headache, dizziness
Sulfamethoxazole-Trimethoprim/TMP-SMZ (Adverse Reactions) - ✔️✔️Blood
dyscrasias
Stevens-Johnson syndrome
, Renal failure
Sulfamethoxazole-Trimethoprim/TMP-SMZ (Drug Interaction) - ✔️✔️Warfarin
Increases anticoagulation
Oral hypoglycemic
Increases hypoglycemia
Sulfamethoxazole-Trimethoprim/TMP-SMZ (class) - ✔️✔️Sulfonamides
Nitrofurantoin (Macrodantin) (class) - ✔️✔️Anti-infective
Nitrofurantoin (Macrodantin) (Actions/uses) - ✔️✔️Inhibits bacterial UTIs caused by E
coli, Klebsiella, Pseudomonas, Proteus vulgaris & morganii, Staph aureus, &
epidermidis, enterococcus, salmonella, shigella
Nitrofurantoin (Macrodantin) (Contraindications) - ✔️✔️Infant <1 mo, hypersensitivity,
anuria, severe renal disease CCr <60 mL/min, term pregnancy, labor, delivery
Nitrofurantoin (Macrodantin) (Adverse reactions) - ✔️✔️Bundle-branch block,
cholestatic jaundice, pseudomembranous coilitis, hepatitis, pancreatitis, anemia,
agranulocytosis, hemolytic anemia, leukopenia, thrombocytopenia, exfoliative
dermatitis, Stevens-Johnson syndrome, superinfection
Phenazopyridine HCL (Pyridium) (Class) - ✔️✔️Urinary Analgesic
Phenazopyridine HCL (Pyridium) (Action) - ✔️✔️Exerts topical analgesic effect on
urinary tract mucosa
Phenazopyridine HCL (Pyridium) (Uses) - ✔️✔️Relief of pain, burning, urgency,
frequency resulting from urinary tract mucosa irritation
Phenazopyridine HCL (Pyridium) (Contraindications) - ✔️✔️Renal & liver insufficiency
Phenazopyridine HCL (Pyridium) (Side Effects) - ✔️✔️h/a, bright orange-colored urine
GI disturbance
Rash & pruritus
Phenazopyridine HCL (Pyridium) (Nursing Implications) - ✔️✔️Teach client how to
avoid UTIs
Take with meals
Explain discoloration of urine (red-orange)
The drug may discolor contact lenses & stain underwear
