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Adrenergic Pharmacology Exam Questions and Answers (Latest Update 2025)
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Adrenergic Pharmacology Exam Questions and Answers (Latest Update 2025)
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Adrenergic Pharmacology ExamQuestions and Answers (Latest Update
2025)
What are the three major organs of Adrenergic Pharmacology
- Correct Answer ✅1. Heart
2. Peripheral vasculature
3. Lungs
Alpha 1 receptors will cause a _______ in blood pressure -
Correct Answer ✅increase
Alpha 2 receptors will cause a _______ in blood pressure -
Correct Answer ✅decrease
Beta 1 receptors are found in the - Correct Answer ✅Heart
Beta 1 receptors will cause a _________ in heart rate - Correct
Answer ✅increase
Beta 2 receptors are found in the - Correct Answer ✅Lungs
,Adrenergic Pharmacology Exam
Questions and Answers (Latest Update
2025)
Increasing heart rate is due to (constriction/dilation) and
leads to (increased/decreased) output - Correct Answer
✅Increasing heart rate is due to constriction and leads to
increased output
Beta 1 receptors increase or decrease the heart rate -
Correct Answer ✅increase heart rate
Catecholamine synthesis, storage, release, and reuptake
pathways Scheme - Correct Answer ✅
The endogenous catecholamines dopamine, norepinephrine,
and epinephrine are all synthesized from - Correct Answer
✅Tyrosine
The rate-limiting step in catecholamine synthesis - Correct
Answer ✅Tyrosine --> dihydroxyphenylalanine (L-DOPA)
is catalyzed by the rate limiting enzyme *Tyrosine
Hydroxylase*
,Adrenergic Pharmacology Exam
Questions and Answers (Latest Update
2025)
What converts L-DOPA to dopamine - Correct Answer
✅Aromatic L-amino acid decarboxylase
Vesicular monoamine transporter (VMAT) translocates
dopamine (and other monoamines) into - Correct Answer
✅synaptic vesicles
In adrenergic neurons, what enzyme converts dopamine to
norepinephrine (NE). - Correct Answer ✅intravesicular
dopamine-β-hydroxylase
What enzyme converts norepinephrine to epinephrine -
Correct Answer ✅*phenylethanolamine N-
methyltransferase (PNMT)*
______ inhibits tyrosine hydroxylase (the rate-limiting enzyme
in catecholamine synthesis) - Correct Answer ✅*α-
Methyltyrosine*
, Adrenergic Pharmacology Exam
Questions and Answers (Latest Update
2025)
T/F Released norepinephrine can stimulate postsynaptic α1-,
β1-, or β2-adrenergic receptors or presynaptic α2-adrenergic
autoreceptors. Released norepinephrine can also be taken up
into presynaptic terminals by the selective NE transporter. -
Correct Answer ✅T
NE in the cytoplasm of the presynaptic neuron can be further
taken up into synaptic vesicles by - Correct Answer ✅VMAT
or degraded to 3, 4-dihydroxyphenylglycoaldehyde (DOPGAL)
by mitochondrion-associated monoamine oxidase (MAO)
Catecholamine (NE, Epi, Dopamine) synthesis - Correct
Answer ✅1. Tyrosine comes in and goes through the pre-
synaptic neuron
2. Tyrosine becomes L-DOPA, which becomes Dopamine
which is then stored by using another transporter, VMAT.
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